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Effect of Cognitive Behavioral Therapy in OCD Highlighted by Neuropsychological Tests and MRI: Pathophysiology and Treatment Outcome Predictors

This study has been completed.
Information provided by (Responsible Party):
University of Aarhus Identifier:
First received: November 14, 2008
Last updated: August 1, 2012
Last verified: August 2012
OCD patients are assessed before and after treatment using diagnostic tools, rating scales neuropsychological assessment and functional and structural MR-scans.

Obsessive-Compulsive Disorder

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Effect of Cognitive Behavioral Therapy in OCD Highlighted by Neuropsychological Tests and MRI: Pathophysiology and Treatment Outcome Predictors

Further study details as provided by University of Aarhus:

Primary Outcome Measures:
  • Y-Bocs [ Time Frame: Before and after treatment approx 20 weeks apart ]

Biospecimen Retention:   Samples With DNA
Full blood

Enrollment: 88
Study Start Date: January 2009
Study Completion Date: July 2012
Primary Completion Date: July 2012 (Final data collection date for primary outcome measure)
OCD patients
Normal Controls


Ages Eligible for Study:   18 Years to 65 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
OCD patients from the primary care clinics in middle Jutland, Denmark

Inclusion Criteria:

1. Steady state medication 3 months prior to the study

Exclusion Criteria:

  1. History of head trauma or other organic brain disease
  2. Pregnancy.
  3. Pacemaker or other ferromagnetic materials in the body.
  4. Comorbid psychiatric illnesses assessed using SCAN- interview (30) other than moderate depression (Ham-D<17) or anxiety disorders.
  5. Antipsychotics
  Contacts and Locations
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Please refer to this study by its identifier: NCT00792038

Aarhus University Hospital, Risskov
Risskov, Denmark, 8240
Sponsors and Collaborators
University of Aarhus
Principal Investigator: Tue BH Hartmann Aarhus University Hospital, Risskov
Study Director: Sanne Kjær Aarhus University Hospital, Risskov
  More Information

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: University of Aarhus Identifier: NCT00792038     History of Changes
Other Study ID Numbers: M-20080161
Study First Received: November 14, 2008
Last Updated: August 1, 2012

Keywords provided by University of Aarhus:
Psychological tests
Magnetic Resonance Imaging
Cognitive therapy

Additional relevant MeSH terms:
Compulsive Personality Disorder
Obsessive-Compulsive Disorder
Compulsive Behavior
Personality Disorders
Mental Disorders
Anxiety Disorders
Impulsive Behavior processed this record on May 25, 2017