Development of Population Norms of the Computerized Neuropsychological Assessment for Effectiveness of the Antipsychotic Treatment in Schizophrenia
|ClinicalTrials.gov Identifier: NCT00789906|
Recruitment Status : Unknown
Verified November 2008 by BeerYaakov Mental Health Center.
Recruitment status was: Recruiting
First Posted : November 13, 2008
Last Update Posted : November 13, 2008
Schizophrenia affects cognition, emotion, and behavior. Neuropsychological assessment enables a better understanding of antipsychotic effectiveness and the brain processes, underlying cognitive functioning in schizophrenia.
Neurocognitive deficits in schizophrenia patients appears to explain up to 61% of the variance of functional outcome and is an important predictor of social reintegration (Peuskens et al, 2005) and independent living activitiy (Green et al, 2004). Impaired social functioning within schizophrenia population has been associated with increased health-care costs. Since social and occupational disability may generate the largest indirect costs of the illness, treatment of cognitive deficits has an enormous impact on the cost and disability associated with schizophrenia (McGurk and Mueser, 2004).
However, the gap between cognitive science and clinical practice limits the implementation of cognitive assessment in the routine evaluation of schizophrenia patients. Pharmaceutical industry initiated numerous large scale, multisite studies on the impact of novel antipsychotics on cognitive deficits in schizophrenia patients.
The aim of this research is to develop population norms of the computerized neuropsychological assessment for effectiveness of the antipsychotic treatment in schizophrenia.
|Condition or disease|
|Study Type :||Observational|
|Estimated Enrollment :||700 participants|
|Official Title:||Development of Population Norms of the Computerized Neuropsychological Assessment for Effectiveness of the Antipsychotic Treatment in Schizophrenia|
|Study Start Date :||July 2008|
350 healthy women , aged from 18 to 89
350 healthy men, aged from 18 to 89
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00789906
|Contact: Semyon Kertzman, MDemail@example.com|
|Beer Yaacov, Israel, 70350|
|Contact: Kertzman 972-8-9776136 firstname.lastname@example.org|
|Principal Investigator: Semion Kertzman, M.D.|