A Study of MK0663/Etoricoxib for Post-Abdominal Hysterectomy Surgery Pain (0663-097)(COMPLETED)
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|ClinicalTrials.gov Identifier: NCT00788710|
Recruitment Status : Completed
First Posted : November 11, 2008
Results First Posted : July 22, 2011
Last Update Posted : December 2, 2015
|Condition or disease||Intervention/treatment||Phase|
|Acute Pain Following a Total Abdominal Hysterectomy||Drug: etoricoxib (MK0663) 120 mg Drug: Comparator: Placebo Drug: etoricoxib (MK0663) 90 mg||Phase 3|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||430 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Double (Participant, Investigator)|
|Official Title:||A Double-Blind, Placebo-Controlled, Multicenter Trial to Study the Efficacy and Tolerability of MK0663/Etoricoxib in the Treatment of Pain After Abdominal Hysterectomy|
|Study Start Date :||October 2008|
|Actual Primary Completion Date :||July 2010|
|Actual Study Completion Date :||July 2010|
Experimental: Etoricoxib 120 mg
etoricoxib (MK0663) 120 mg (2 60 mg tablets) and 1 placebo tablet once daily on Days 1-5. Total treatment is 5 days.
Drug: etoricoxib (MK0663) 120 mg
120 mg of etoricoxib (MK0663) for a total of 5 days
Other Name: Arcoxia
Experimental: Etoricoxib 90 mg
etoricoxib (MK0663) 90 mg tablet and 2 placebo tablets once daily on Days 1-5. Total treatment is 5 days.
Drug: etoricoxib (MK0663) 90 mg
90 mg of etoricoxib (MK0663) for a total of 5 days
Placebo Comparator: Placebo
Placebo- 3 tablets once daily
Drug: Comparator: Placebo
Placebo tablets once daily on Days 1-5. Total treatment is 5 days.
- Average Pain Intensity at Rest Over Days 1 to 3 [ Time Frame: 3 Days ]Pain intensity at rest was measured on a 0- to 10-point scale: 0=no pain, to 10=pain as bad as you can imagine.
- Average Total Daily Dose of Morphine Over Days 1 to 3 [ Time Frame: 3 days ]
- Average Elicited Pain Upon Sitting Over Days 1 to 3 [ Time Frame: 3 days ]Elicited pain upon sitting was measured on a 0- to 10-point scale: 0=no pain, to 10=pain as bad as you can imagine.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00788710
|Study Director:||Medical Monitor||Merck Sharp & Dohme Corp.|