Real Life Effectiveness in Patients With Not Optimally Controlled Asthma
A non-interventional study to explore actual asthma control status in real-life environment and to observe the efficacy after stepped-up to Symbicort SMART or various identical regimens.
The study will be implemented by screening asthmatic patients from respiratory clinics to identify those not optimally controlled and required stepping up the controllers to initiate, or to titrate dose of, ICS/LABA including Symbicort.
|Study Design:||Time Perspective: Prospective|
|Official Title:||Real Life Effectiveness in Patients With Not Optimally Controlled Asthma: Symbicort SMART, or Other ICS/LABA With as Needed SABA|
- Change in ACQ score from baseline to the mean of all available data from the follow up visits [ Time Frame: wk 4±1; wk 12~16 ] [ Designated as safety issue: No ]
- Change in the individual asthma control status & pulmonary function from enrollment [ Time Frame: wk 4±1; wk 12~16 ] [ Designated as safety issue: No ]
- Dose/usage of ICS/LABA and relievers & Patient compliance [ Time Frame: wk 4±1; wk 12~16 ] [ Designated as safety issue: No ]
- Medical resource utilization [ Time Frame: wk 4±1; wk 12~16; 6 month; 12 month ] [ Designated as safety issue: No ]
|Study Start Date:||October 2008|
|Study Completion Date:||May 2011|
|Primary Completion Date:||May 2011 (Final data collection date for primary outcome measure)|
Asthma patients who were partly controlled or uncontrolled, need to step up, or adjust dose of the controller medications to ICS/LABA
Please refer to this study by its ClinicalTrials.gov identifier: NCT00784953
|Study Director:||Robin Meng, MD, PhD||AstraZeneca Taiwan|
|Principal Investigator:||Jia-Horng Wang, MD||Taipei Veterans General Hospital, Taiwan|