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Hypnotherapeutic Olfactory Conditioning for Posttraumatic Stress Disorder (PTSD)

This study has been completed.
ClinicalTrials.gov Identifier:
First Posted: November 4, 2008
Last Update Posted: November 20, 2015
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
Herzog Hospital
Chronic combat-related posttraumatic stress disorder can be difficult to treat. The investigators believe that hypnosis, with a stress on the sensation of scent which often plays a role in the traumatic memories, can offer help for victims of this disorder who continue to suffer after receiving other treatments.

Condition Intervention
Posttraumatic Stress Disorder Behavioral: Hypnotherapeutic Olfactory Conditioning (HOC)

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Hypnotherapeutic Olfactory Conditioning for Chronic Combat-Related Posttraumatic Stress Disorder

Resource links provided by NLM:

Further study details as provided by Herzog Hospital:

Primary Outcome Measures:
  • Impact of Event Scale [ Time Frame: Baseline, 6 weeks, 6 months, one year ]

Secondary Outcome Measures:
  • Beck Depression Inventory [ Time Frame: Baseline, 6 weeks, 6 months, one year ]
  • Dissociative Experience Scale [ Time Frame: Baseline, 6 weeks, 6 months, one year ]

Enrollment: 36
Study Start Date: January 2005
Study Completion Date: February 2007
Primary Completion Date: February 2007 (Final data collection date for primary outcome measure)
Detailed Description:
Our study examines the effect of hypnosis upon 36 individuals who suffer from posttraumatic stress disorder incurred in battles or training. The hypnotherapy stresses elements of odor, both in conditioning the subject to relate certain pleasant odors with security and calm, and in gradually reexposing the patient to the olfactory aspects of the traumatic memories. All subjects are taken form the Israel Defense Forces Mental Health Clinic, treated with 6 one-and-a-half-hour hypnotherapy sessions, and evaluated at baseline, end of treatment, after 6 months, and after 12 months, on a battery of clinical scales.

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  1. A diagnosis of chronic combat-related PTSD according to DSM-IV criteria (APA, 1994), as determined by semi-structured psychiatric interview conducted by a psychiatrist with over ten years of experience treating PTSD
  2. Flashbacks and/or panic attacks with olfactory components
  3. Prior attempt at treatment with unsatisfactory results
  4. Competence and agreement to sign an informed consent.

Exclusion Criteria:

  1. Evidence of psychosis
  2. Severe traumatic brain injury
  3. Post-concussion syndrome
  4. Uncontrolled substance abuse.
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00784771

Combat Stress Reaction Unit, Medical Corps, Mental Health Department, Israel Defense Forces
Tel Hashomer, Ramat Gan, Israel, 71700
Sponsors and Collaborators
Herzog Hospital
  More Information

Responsible Party: Dr. Pesach Lichtenberg, Herzog Hospital
ClinicalTrials.gov Identifier: NCT00784771     History of Changes
Other Study ID Numbers: lichtenberg4 CTIL
First Submitted: November 3, 2008
First Posted: November 4, 2008
Last Update Posted: November 20, 2015
Last Verified: November 2008

Keywords provided by Herzog Hospital:

Additional relevant MeSH terms:
Stress Disorders, Traumatic
Stress Disorders, Post-Traumatic
Pathologic Processes
Trauma and Stressor Related Disorders
Mental Disorders