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Middle and Inner Ear Malformation in Children With Velocardiofacial Syndrome

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00784173
First Posted: November 3, 2008
Last Update Posted: November 3, 2008
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
Pontificia Universidade Catolica de Sao Paulo
  Purpose
Middle and inner ear malformations on two boys with velocardiofacial syndrome are discussed.Special attention should be given to the presence of hearing loss due to middle and inner ear malformations, in addition to frequent conductive hearing loss regarding mastoid and middle ear inflammatory processes.

Condition
Ear Malformations in the Velocardiofacial Syndrome

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Middle and Inner Ear Malformation in Children With Velocardiofacial Syndrome

Resource links provided by NLM:


Further study details as provided by Pontificia Universidade Catolica de Sao Paulo:

Enrollment: 2
Study Start Date: January 2007
Study Completion Date: June 2007
Primary Completion Date: March 2007 (Final data collection date for primary outcome measure)
Detailed Description:
Two boys with clinical signs of velocardiofacial syndrome, at ages of 4.7 and 6,7 years old are the subjects of this study.Audiological evaluation, including pure tone audiometry, tympanometry, acoustical reflex, and Computerized Tomography of temporal bones, and analyses of DNA sample with markers of 22q11 region were performed.
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Children with velocardiofacial syndrome
Criteria

Inclusion Criteria:

  • Subjects with velocardiofacial syndrome
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00784173


Sponsors and Collaborators
Pontificia Universidade Catolica de Sao Paulo
Investigators
Principal Investigator: Alfredo Tabith-Junior, MD Pontificia Universidade Católica de São Paulo
  More Information

Responsible Party: Alfredo Tabith Junior, Pontificia Universidade Catolica de São Paulo
ClinicalTrials.gov Identifier: NCT00784173     History of Changes
Other Study ID Numbers: Unique protocol
First Submitted: October 31, 2008
First Posted: November 3, 2008
Last Update Posted: November 3, 2008
Last Verified: October 2008

Keywords provided by Pontificia Universidade Catolica de Sao Paulo:
Syndrome
Velocardiofacial
Middle ear
Inner ear
Malformation

Additional relevant MeSH terms:
Syndrome
Congenital Abnormalities
DiGeorge Syndrome
Disease
Pathologic Processes
22q11 Deletion Syndrome
Craniofacial Abnormalities
Musculoskeletal Abnormalities
Musculoskeletal Diseases
Heart Defects, Congenital
Cardiovascular Abnormalities
Cardiovascular Diseases
Heart Diseases
Lymphatic Abnormalities
Lymphatic Diseases
Abnormalities, Multiple
Chromosome Disorders
Genetic Diseases, Inborn
Hypoparathyroidism
Parathyroid Diseases
Endocrine System Diseases