We updated the design of this site on December 18, 2017. Learn more.
ClinicalTrials.gov Menu

Middle and Inner Ear Malformation in Children With Velocardiofacial Syndrome

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT00784173
Recruitment Status : Completed
First Posted : November 3, 2008
Last Update Posted : November 3, 2008
Information provided by:

Study Description
Brief Summary:
Middle and inner ear malformations on two boys with velocardiofacial syndrome are discussed.Special attention should be given to the presence of hearing loss due to middle and inner ear malformations, in addition to frequent conductive hearing loss regarding mastoid and middle ear inflammatory processes.

Condition or disease
Ear Malformations in the Velocardiofacial Syndrome

Detailed Description:
Two boys with clinical signs of velocardiofacial syndrome, at ages of 4.7 and 6,7 years old are the subjects of this study.Audiological evaluation, including pure tone audiometry, tympanometry, acoustical reflex, and Computerized Tomography of temporal bones, and analyses of DNA sample with markers of 22q11 region were performed.

Study Design

Study Type : Observational
Actual Enrollment : 2 participants
Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Middle and Inner Ear Malformation in Children With Velocardiofacial Syndrome
Study Start Date : January 2007
Primary Completion Date : March 2007
Study Completion Date : June 2007

Groups and Cohorts

Outcome Measures

Eligibility Criteria

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Children with velocardiofacial syndrome

Inclusion Criteria:

  • Subjects with velocardiofacial syndrome
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00784173

Sponsors and Collaborators
Pontificia Universidade Catolica de Sao Paulo
Principal Investigator: Alfredo Tabith-Junior, MD Pontificia Universidade Católica de São Paulo
More Information

Responsible Party: Alfredo Tabith Junior, Pontificia Universidade Catolica de São Paulo
ClinicalTrials.gov Identifier: NCT00784173     History of Changes
Other Study ID Numbers: Unique protocol
First Posted: November 3, 2008    Key Record Dates
Last Update Posted: November 3, 2008
Last Verified: October 2008

Keywords provided by Pontificia Universidade Catolica de Sao Paulo:
Middle ear
Inner ear

Additional relevant MeSH terms:
Congenital Abnormalities
DiGeorge Syndrome
Pathologic Processes
22q11 Deletion Syndrome
Craniofacial Abnormalities
Musculoskeletal Abnormalities
Musculoskeletal Diseases
Heart Defects, Congenital
Cardiovascular Abnormalities
Cardiovascular Diseases
Heart Diseases
Lymphatic Abnormalities
Lymphatic Diseases
Abnormalities, Multiple
Chromosome Disorders
Genetic Diseases, Inborn
Parathyroid Diseases
Endocrine System Diseases