Measurement of the Eye's Blood Vessels Using the Dynamic Vessel Analyzer (DVA)
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ClinicalTrials.gov Identifier: NCT00783029 |
Recruitment Status
:
Completed
First Posted
: October 31, 2008
Last Update Posted
: February 7, 2012
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Condition or disease |
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Healthy |
Study Type : | Observational |
Actual Enrollment : | 87 participants |
Observational Model: | Case-Only |
Time Perspective: | Prospective |
Official Title: | Reproducibility of Dynamic Vessel Analyzer Measurements and Establishment of Standards |
Study Start Date : | October 2008 |
Actual Primary Completion Date : | December 2011 |
Actual Study Completion Date : | December 2011 |
Group/Cohort |
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Healthy Subjects
Healthy participants between the ages of 21 and 65 years old.
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- To characterize changes in the diameter of retinal blood vessels to a light-induced flicker stimulus in healthy subjects on two separate visits. [ Time Frame: 1 Year ]
- To compare retinal vasodilator responses to brachial reactive hyperemic responses. [ Time Frame: 1 Year ]

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Ages Eligible for Study: | 21 Years to 65 Years (Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | Yes |
Sampling Method: | Non-Probability Sample |
Inclusion Criteria:
- Healthy Individuals
- Age: 21 to 65 years
- Non-smokers
- Non-obese
Exclusion Criteria:
- History of cardiovascular, pulmonary, peripheral vascular disease, renal, prostate, and urinary retention disease; Hypertension; Narrow angle Glaucoma or Age Related Macular Degeneration.
- Pregnancy
- Inability to fixate using eye device
- Does not wish to participate

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00783029
United States, Pennsylvania | |
Penn State Milton S. Hershey Medical Center | |
Hershey, Pennsylvania, United States, 17033 |
Principal Investigator: | Kerstin Bettermann, MD, PhD | Penn State College of Medicine |
Responsible Party: | Kerstin Bettermann, MD, PhD, Penn State University |
ClinicalTrials.gov Identifier: | NCT00783029 History of Changes |
Other Study ID Numbers: |
HMC29113 IRB # 29113 |
First Posted: | October 31, 2008 Key Record Dates |
Last Update Posted: | February 7, 2012 |
Last Verified: | February 2012 |
Keywords provided by Kerstin Bettermann, Penn State University:
Vasodilation Vessel Reactivity Dynamic Vessel Analyzer Retina |
Additional relevant MeSH terms:
Glucuronyl glucosamine glycan sulfate Anticoagulants Hypolipidemic Agents Antimetabolites Molecular Mechanisms of Pharmacological Action |
Lipid Regulating Agents Fibrinolytic Agents Fibrin Modulating Agents Hypoglycemic Agents Physiological Effects of Drugs |