Trial record 3 of 273 for:    Postpartum Depression AND Postpartum Depression | "Depression" AND "Depression"

Postpartum Anemia and Postpartum Depression (PPADS)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00782912
Recruitment Status : Completed
First Posted : October 31, 2008
Last Update Posted : April 22, 2015
Information provided by (Responsible Party):
St. Michael's Hospital, Toronto

Brief Summary:
Postpartum anemia (PPA) and Postpartum depression (PPD) are common afflictions affecting women after childbirth. Both disorders have a significant impact on women's health and functional status. Despite common symptoms and characteristics, a link between these entities has not been adequately studied. The objective of this study is to determine whether postpartum anemia is an independent risk factor for the development of postpartum depression. This prospective cohort study will include all women delivered by elective term cesarean delivery. Hemoglobin and iron levels will be measured, standardized questionnaires for assessment of PPD, functional status and lactation will be administered before discharge and at 3 & 6 weeks post partum. Hemoglobin levels at each time point will be analyzed for correlation with depressive symptoms, functional status and lactation success.

Condition or disease
Postpartum Depression

Study Type : Observational
Actual Enrollment : 103 participants
Observational Model: Case Control
Time Perspective: Prospective
Official Title: Is Postpartum Anemia an Independent Risk Factor for Development of Postpartum Depression?
Study Start Date : November 2008
Actual Primary Completion Date : October 2014
Actual Study Completion Date : October 2014

Resource links provided by the National Library of Medicine

Primary Outcome Measures :
  1. Incidence of postpartum depression [ Time Frame: 0-6 weeks postpartum ]

Secondary Outcome Measures :
  1. Mean Edinburgh Postnatal Depression Scale results [ Time Frame: 0-6 weeks postpartum ]
  2. Functional status [ Time Frame: 0-6 weeks postpartum ]
  3. Lactation success [ Time Frame: 0-6 weeks postpartum ]

Biospecimen Retention:   Samples With DNA
Blood samples

Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Women after term elective cesarean section

Inclusion Criteria:

  • Women after term elective cesarean section

Exclusion Criteria:

  • age < 16 years, preterm (< 37 weeks) delivery, multiple gestation, symptomatic anemia necessitating blood transfusion, significant fetal anomalies or infant not discharged with mother for other reason, preexisting severe chronic maternal illness, preexisting maternal depression and/or current use of antidepressants, other psychiatric illness (e.g. bipolar disease, schizophrenia) or preexisting hemoglobinopathy

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00782912

Canada, Ontario
St. Michael's Hospital
Toronto, Ontario, Canada, M5B1W8
Sponsors and Collaborators
St. Michael's Hospital, Toronto
Principal Investigator: Howard Berger, MD St. Michael's Hospital, Toronto

Responsible Party: St. Michael's Hospital, Toronto Identifier: NCT00782912     History of Changes
Other Study ID Numbers: REB 08-155
First Posted: October 31, 2008    Key Record Dates
Last Update Posted: April 22, 2015
Last Verified: April 2015

Keywords provided by St. Michael's Hospital, Toronto:
postpartum anemia, postpartum depression

Additional relevant MeSH terms:
Depressive Disorder
Depression, Postpartum
Behavioral Symptoms
Mood Disorders
Mental Disorders
Hematologic Diseases
Puerperal Disorders
Pregnancy Complications