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Heart Rate Variability Change After Liver Transplantation

This study has been completed.
Information provided by (Responsible Party):
National Taiwan University Hospital Identifier:
First received: October 22, 2008
Last updated: December 22, 2013
Last verified: December 2013
Cirrhotic cardiomyopathy describes a hyperdynamic state with the presentation of high cardiac output and low systemic vascular resistance. And the latent heart failure becomes obvious under physiologic and pharmacologic stress. The goal of our study is to assess the effects of liver transplantation on the heart rate variability in patients with end stage liver disease.

Liver Transplantation

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Effects of Liver Transplantation on the Heart Rate Variability in Patients With End-Stage Liver Disease

Resource links provided by NLM:

Further study details as provided by National Taiwan University Hospital:

Primary Outcome Measures:
  • Multiscale entropy [ Time Frame: 6 months ]
    Multiscale entropy was measured at nine time points: 1. preoperative, 2. postoperative day 1, 3. postoperative day 2, 4. postoperative day 3, 5. postoperative day 4, 6. postoperative day 7, 7. postoperative day 14, 8. postoperative 3 months, 9. postoperative 6 months

Enrollment: 30
Study Start Date: October 2008
Study Completion Date: January 2010
Primary Completion Date: January 2010 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   18 Years to 70 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients with end stage liver disease undergoing liver transplantation

Inclusion Criteria:

  • Age:18-70y/o receiving liver transplantation

Exclusion Criteria:

  • History of cardiovascular disease
  Contacts and Locations
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Please refer to this study by its identifier: NCT00778687

National Taiwan University Hospital
Taipei, Taiwan
Sponsors and Collaborators
National Taiwan University Hospital
  More Information

Responsible Party: National Taiwan University Hospital Identifier: NCT00778687     History of Changes
Other Study ID Numbers: 200809046R
Study First Received: October 22, 2008
Last Updated: December 22, 2013 processed this record on August 17, 2017