Longitudinal Study of Symptoms in Colorectal Cancer
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT00777192|
Recruitment Status : Terminated (Terminated at continuing review)
First Posted : October 22, 2008
Last Update Posted : May 29, 2019
|Condition or disease||Intervention/treatment|
|Colorectal Cancer||Behavioral: Questionnaires|
If you agree to take part in this study, you will complete 5 questionnaires during a regularly scheduled visit. The questionnaires are designed to measure pain and other symptoms, your mood, and your quality of life.
You will also give a tissue sample by inserting a cotton tipped swab into your mouth and rubbing firmly against the inside of your cheek or underneath your lower or upper lip for about 1 minute at the most.
Completing the 5 questionnaires and the swab sample should take about 30 minutes.
Length of Study:
After you complete the questionnaires and the swab sample collection, your active participation in this study will be over.
This is an investigational study.
Up to 500 patients will take part in this study. All will be enrolled at MD Anderson.
|Study Type :||Observational|
|Actual Enrollment :||509 participants|
|Official Title:||Prospective Study of Symptoms Related to Oxaliplatin-based Regimens in the Treatment of Colorectal Cancer|
|Actual Study Start Date :||August 2008|
|Actual Primary Completion Date :||December 27, 2018|
|Actual Study Completion Date :||December 27, 2018|
Symptoms in Colorectal Cancer
Colorectal Cancer Patients Receiving Oxaliplatin Chemotherapy
20 Minute Questionnaires beginning Visit 1, to measure pain/other symptoms, mood, and quality of life
- Association between inflammatory cytokines and development of treatment-related symptom burden in colorectal cancer patients [ Time Frame: 5 Years ]
- Primary afferent function in colorectal cancer patients receiving chemotherapy by quantitative sensory testing over time [ Time Frame: 5 Years ]
- Neurocognitive and neuropsychiatric symptoms in colorectal cancer patients [ Time Frame: Neuropsychological test battery at baseline and 3 + 6 month follow ups ]
Biospecimen Retention: Samples With DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00777192
|United States, Texas|
|University of Texas MD Anderson Cancer Center|
|Houston, Texas, United States, 77030|
|Principal Investigator:||Xin Shelley Wang, MD. MPH||M.D. Anderson Cancer Center|