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Trial record 60 of 337 for:    Charcot Marie Tooth

Nerve Entrapment in Diabetic Patients

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00775333
Recruitment Status : Completed
First Posted : October 20, 2008
Last Update Posted : October 20, 2008
Information provided by:
Skane University Hospital

Brief Summary:
The aim of this study is in a prospective, consecutive series of diabetic patients with carpal tunnel syndrome, who are then age and gender matched with non-diabetic patients having idiopathic carpal tunnel syndrome to compare the clinical results after carpal tunnel release.

Condition or disease Intervention/treatment
Carpal Tunnel Syndrome Entrapment Neuropathies Nerve Compression Syndromes Diabetes Complications Procedure: Outcome after carpal tunnel release

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Study Type : Observational
Actual Enrollment : 67 participants
Observational Model: Case Control
Time Perspective: Prospective
Official Title: Clinical Outcomes of Surgical Release Among Diabetic Patients With Carpal Tunnel Syndrome. A Prospective Study With Matched Controls
Study Start Date : December 2003
Actual Study Completion Date : April 2008

Group/Cohort Intervention/treatment
Patients with diabetes and carpal tunnel syndrome
Non-diabetic patients with carpal tunnel syndrome
Procedure: Outcome after carpal tunnel release
Follow the outcome after standard carpal tunnel release in diabetic and non-diabetic patients

Primary Outcome Measures :
  1. Sensory function (Semmens-Weinstein), motor function (Abductor Pollicis Brevis (APB)-strength, grip strength) [ Time Frame: Baseline, 6 weeks, 12 weeks, 52 weeks ]

Secondary Outcome Measures :
  1. Pillar pain, cold intolerance, and patient satisfaction. [ Time Frame: Baseline, 6 weeks, 12 weeks, 52 weeks ]

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 80 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients referred to a specialized hand clinic

Inclusion Criteria:

  • Diagnosis was based on clinical history and symptoms of carpal tunnel syndrome
  • Confirmed by nerve conduction studies.

Exclusion Criteria:

  • Other focal nerve entrapments
  • Cervical radiculopathy
  • Inflammatory joint disease
  • Renal failure
  • Thyroid disorders
  • Previous wrist fracture
  • Long-term exposure to vibrating tools.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00775333

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Dept. of Hand Surgery, Malmo University Hospital
Malmo, Sweden, 205 02
Sponsors and Collaborators
Skane University Hospital
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Principal Investigator: Lars Dahlin, PHD

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Responsible Party: Niels Thomsen, MD, Dept. of Hand Surgery, Malmo University Hospital, Sweden Identifier: NCT00775333     History of Changes
Other Study ID Numbers: LU 508-03
First Posted: October 20, 2008    Key Record Dates
Last Update Posted: October 20, 2008
Last Verified: October 2008
Keywords provided by Skane University Hospital:
Carpal Tunnel Syndrome
APB strength
Sensory Function
Pillar Pain
Cold Intolerance
Patient Satisfaction
Additional relevant MeSH terms:
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Nerve Compression Syndromes
Charcot-Marie-Tooth Disease
Hereditary Sensory and Motor Neuropathy
Carpal Tunnel Syndrome
Diabetes Complications
Pathologic Processes
Median Neuropathy
Peripheral Nervous System Diseases
Neuromuscular Diseases
Nervous System Diseases
Cumulative Trauma Disorders
Sprains and Strains
Wounds and Injuries
Diabetes Mellitus
Endocrine System Diseases
Nervous System Malformations
Heredodegenerative Disorders, Nervous System
Neurodegenerative Diseases
Congenital Abnormalities
Genetic Diseases, Inborn