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Mastering Hospital Antimicrobial Resistance and Its Spread Into the Community (MOSAR)

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified October 2008 by Tel-Aviv Sourasky Medical Center.
Recruitment status was:  Not yet recruiting
Sponsor:
ClinicalTrials.gov Identifier:
NCT00773799
First Posted: October 16, 2008
Last Update Posted: October 16, 2008
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
Tel-Aviv Sourasky Medical Center
  Purpose
Data on occurrence of antimicrobial resistant bacteria acquisition in rehabilitation centers will be collected. After removal of patient identifiers, information regarding the patients population will be entered into electronic sheet. The phase will last twelve months in each center.

Condition
ESBL Infection Methicillin-Resistant Staphylococcus Aureus

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Retrospective
Official Title: Mastering Hospital Antimicrobial Resistance and Its Spread Into the Community

Resource links provided by NLM:


Further study details as provided by Tel-Aviv Sourasky Medical Center:

Primary Outcome Measures:
  • A rehabilitation center's department in which the hospitalized patients are older then 18 years old. [ Time Frame: 1 YEAR ]

Estimated Enrollment: 1200
Study Start Date: October 2008
Estimated Study Completion Date: January 2014
Estimated Primary Completion Date: October 2009 (Final data collection date for primary outcome measure)
Groups/Cohorts
rehabilitation center's hospitalized patients

Detailed Description:

All patients admitted to the department will be examined on admission, two weeks latter and monthly by obtaining nares and perirectal cultures. These cultures will be processed for detection the target organisms. This activity is part of the good medical practice and is performed on routine basis in various hospital units

Epidemiological data will be collected from patient records. This data will be stored after removal of all patients' identifiers. These data will be transferred for analysis to Tel Aviv Medical Center

  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
A rehabilitation center's department in which the hospitalized patients are older then 18 years old.
Criteria

Inclusion Criteria:

  • Hospitalized patients are older then 18 years old

Exclusion Criteria:

  • Age 18 years or less
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00773799


Contacts
Contact: yaffa lerman, MD 97252-4266910 yaffale@tasmc.health.gov.il

Locations
Israel
Tasmc Not yet recruiting
Tel-aviv, Israel, 64239
Contact: Yaffa lerman, md    97252-4266910    yaffale@tasmc.health.gov.il   
Sponsors and Collaborators
Tel-Aviv Sourasky Medical Center
Investigators
Principal Investigator: Yehuda carmeli, MD MPH TASMC
  More Information

Publications:
Vovko P, Retelj M, Cretnik TZ, Jutersek B, Harlander T, Kolman J, Gubina M. Risk factors for colonization with methicillin-resistant Staphylococcus aureus in a long-term-care facility in Slovenia. Infect Control Hosp Epidemiol. 2005 Feb;26(2):191-5.
Lucet JC, Grenet K, Armand-Lefevre L, Harnal M, Bouvet E, Regnier B, Andremont A. High prevalence of carriage of methicillin-resistant Staphylococcus aureus at hospital admission in elderly patients: implications for infection control strategies. Infect Control Hosp Epidemiol. 2005 Feb;26(2):121-6.
Ben-Ami R, Schwaber MJ, Navon-Venezia S, Schwartz D, Giladi M, Chmelnitsky I, Leavitt A, Carmeli Y. Influx of extended-spectrum beta-lactamase-producing enterobacteriaceae into the hospital. Clin Infect Dis. 2006 Apr 1;42(7):925-34. Epub 2006 Feb 27.
Stelfox HT, Bates DW, Redelmeier DA. Safety of patients isolated for infection control. JAMA. 2003 Oct 8;290(14):1899-905.
Campbell M, Fitzpatrick R, Haines A, Kinmonth AL, Sandercock P, Spiegelhalter D, Tyrer P. Framework for design and evaluation of complex interventions to improve health. BMJ. 2000 Sep 16;321(7262):694-6.
Pope C, van Royen P, Baker R. Qualitative methods in research on healthcare quality. Qual Saf Health Care. 2002 Jun;11(2):148-52.
Bartholomew LK, Parcel GS, Kok G. Intervention mapping: a process for developing theory- and evidence-based health education programs. Health Educ Behav. 1998 Oct;25(5):545-63. Review.
van Bokhoven MA, Kok G, van der Weijden T. Designing a quality improvement intervention: a systematic approach. Qual Saf Health Care. 2003 Jun;12(3):215-20.
Smith DL, Dushoff J, Perencevich EN, Harris AD, Levin SA. Persistent colonization and the spread of antibiotic resistance in nosocomial pathogens: resistance is a regional problem. Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3709-14. Epub 2004 Feb 25. Erratum in: Proc Natl Acad Sci U S A. 2004 Apr 13;101(15):5696.

Responsible Party: yehuda carmeli, TASMC
ClinicalTrials.gov Identifier: NCT00773799     History of Changes
Other Study ID Numbers: TASMC-08-YC-239-CTIL
First Submitted: October 6, 2008
First Posted: October 16, 2008
Last Update Posted: October 16, 2008
Last Verified: October 2008

Keywords provided by Tel-Aviv Sourasky Medical Center:
To define activities and patient characteristics likely to lead to dissemination of resistant bacteria in rehabilitation centers and
To define specific risk factors for acquisition of resistant bacteria (ESBL producers and MRSA) in rehabilitation centers.
ESBL producers
MRSA

Additional relevant MeSH terms:
Staphylococcal Infections
Gram-Positive Bacterial Infections
Bacterial Infections
Anti-Infective Agents
Anti-Bacterial Agents


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