Intraoperative and Postoperative Analgesia for Laparoscopic Surgery.

This study has been completed.
Information provided by:
Rambam Health Care Campus Identifier:
First received: May 21, 2008
Last updated: September 21, 2010
Last verified: July 2010
Main Hypothesis: laparoscopic surgery is very painful to patient during and after surgery. We would like to compare different analgesic methods.

Condition Intervention Phase
Drug: morphine
Drug: intrathecal analgesia (morphine)
Drug: general anesthesia (fentanyl)
Phase 4

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Single Blind (Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Intraoperative and Postoperative Analgesia for Laparoscopic Surgery.

Resource links provided by NLM:

Further study details as provided by Rambam Health Care Campus:

Primary Outcome Measures:
  • Good analgesic method with minimal side effect. [ Designated as safety issue: Yes ]

Estimated Enrollment: 40
Study Start Date: October 2007
Study Completion Date: September 2009
Primary Completion Date: September 2009 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: 1
General anesthesia + I.V pca
Drug: general anesthesia (fentanyl)
general anesthesia alone
Experimental: 2
General anesthesia + spinal analgesia + I.V pca
Drug: morphine
Single dose: 0.1-0.5 mg
Drug: intrathecal analgesia (morphine)
0.1-0.5 mg of morphine


Ages Eligible for Study:   18 Years to 80 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Laparoscopic (general) Surgery
  • Age>18
  • ASA<4
  • Morning surgery

Exclusion Criteria:

  • Patient refusal
  • contra-indication for treatment
  Contacts and Locations
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Please refer to this study by its identifier: NCT00772187

Rambam Health Care Campus
Haifa, Israel, 31096
Sponsors and Collaborators
Rambam Health Care Campus
  More Information

Responsible Party: Dror Segal, M.D, Rambam Health Care Campus Identifier: NCT00772187     History of Changes
Other Study ID Numbers: Rambam2690CTIL 
Study First Received: May 21, 2008
Last Updated: September 21, 2010
Health Authority: Israel: Israeli Health Ministry Pharmaceutical Administration

Keywords provided by Rambam Health Care Campus:
Laparoscopic surgery (general surgery).

Additional relevant MeSH terms:
Analgesics, Opioid
Central Nervous System Depressants
Peripheral Nervous System Agents
Physiological Effects of Drugs
Sensory System Agents processed this record on May 24, 2016