Radical Prostatectomy and Perioperative Fluid Therapy
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|ClinicalTrials.gov Identifier: NCT00771966|
Recruitment Status : Completed
First Posted : October 15, 2008
Last Update Posted : October 22, 2012
The optimal amount of fluid a patient need under surgery is not clear. Both to much and to little fluid can damage the organ functions.
A strategy called "Goal directed therapy", where the fluid amount a patient need is guided by the stroke volume, has shown to minimize post-operative nausea and vomiting.
The investigators intend to investigate if patients treated after these standards, has a better outcome then patients treated after normal regimes, regarding post-operative orthostatic-intolerance.
|Condition or disease||Intervention/treatment||Phase|
|Prostate Cancer||Procedure: Standard therapy Procedure: Maximization of cardiac stroke volume with fluid infusion||Phase 4|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||44 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||Double (Investigator, Outcomes Assessor)|
|Official Title:||Radical Prostatectomy and Perioperative Fluid Therapy|
|Study Start Date :||October 2008|
|Actual Primary Completion Date :||October 2009|
|Actual Study Completion Date :||October 2009|
|Placebo Comparator: Standard treatment||
Procedure: Standard therapy
|Active Comparator: SV maximization||
Procedure: Maximization of cardiac stroke volume with fluid infusion
Maximization of cardiac stroke volume with fluid infusion
- To investigate orthostatic cardiovascular response and orthostatic intolerance in patients after removal of the prostate [ Time Frame: 6 hours ]
- Investigate intraoperative haemodynamics [ Time Frame: Intraoperative ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00771966
|Dept of anesthesiology, Rigshospitalet|