Preoperative Assessment of Aortic Valve Stenosis and Coronary Artery Disease
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|ClinicalTrials.gov Identifier: NCT00767013|
Recruitment Status : Unknown
Verified April 2013 by Prof. Paul Erne, Luzerner Kantonsspital.
Recruitment status was: Recruiting
First Posted : October 6, 2008
Last Update Posted : April 17, 2013
|Condition or disease||Intervention/treatment||Phase|
|Aortic Valve Stenosis Coronary Disease||Other: DSCT, TTE||Not Applicable|
Until now invasive coronary angiography has established itself for the assessment of symptomatic aortic valve stenosis. Literature shows a good correlation between MSCT, MRI, TTE and TEE for evaluating the severity of the aortic valve stenosis.
The dual-source computed tomography (DSCT) is capable of assessing coronary arteries with a high sensitivity and specificity in term of relevant stenosis (>50%), due to its excellent spatial and temporal resolution. This study includes the assessment of patients with symptomatic valve stenosis. The severity of the aortic valve stenosis is being assessed by DSCT and TTE. Significant coronary artery stenosis and its localisation are assessed by DSCT and invasive coronary angiography. We examine the correlation between DSCT on one side and either TTE or invasive coronary angiography on the other.
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||65 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||Preoperative Assessment of Aortic Valve Stenosis and Coronary Artery Disease: Dual-source Computed Tomography Compared With Invasive Coronary Angiography and Transthoracic Echocardiography|
|Study Start Date :||May 2007|
|Estimated Primary Completion Date :||December 2013|
U.S. FDA Resources
Experimental: AVS, CAD
Other: DSCT, TTE
One assessment each
- Quality of cardiac imaging in computed tomography [ Time Frame: After comparison of imaging measurements ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00767013
|Luzerner Kantonsspital, Department of Cardiology||Recruiting|
|Lucerne, Luzern, Switzerland, 6000|
|Contact: Paul Erne, MD ++41 41 205 51 06 firstname.lastname@example.org|
|Contact: Christoph Auf der Maur, MD ++41 41 2005 51 48|
|Principal Investigator: Paul Erne, MD|
|Sub-Investigator: Christoph Auf der Maur, MD|
|Principal Investigator:||Paul Erne, MD||Luzerner Kantonsspital|