Preoperative Assessment of Aortic Valve Stenosis and Coronary Artery Disease
Recruitment status was Recruiting
We sought to determine whether the dual-source computed tomography assessment of aortic valve stenosis and coronary artery disease is equivalent to or even better than conventional invasive coronary angiography and transthoracic echocardiography.
|Study Design:||Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Diagnostic
|Official Title:||Preoperative Assessment of Aortic Valve Stenosis and Coronary Artery Disease: Dual-source Computed Tomography Compared With Invasive Coronary Angiography and Transthoracic Echocardiography|
- Quality of cardiac imaging in computed tomography [ Time Frame: After comparison of imaging measurements ] [ Designated as safety issue: No ]
|Study Start Date:||May 2007|
|Estimated Primary Completion Date:||December 2013 (Final data collection date for primary outcome measure)|
Until now invasive coronary angiography has established itself for the assessment of symptomatic aortic valve stenosis. Literature shows a good correlation between MSCT, MRI, TTE and TEE for evaluating the severity of the aortic valve stenosis.
The dual-source computed tomography (DSCT) is capable of assessing coronary arteries with a high sensitivity and specificity in term of relevant stenosis (>50%), due to its excellent spatial and temporal resolution. This study includes the assessment of patients with symptomatic valve stenosis. The severity of the aortic valve stenosis is being assessed by DSCT and TTE. Significant coronary artery stenosis and its localisation are assessed by DSCT and invasive coronary angiography. We examine the correlation between DSCT on one side and either TTE or invasive coronary angiography on the other.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00767013
|Luzerner Kantonsspital, Department of Cardiology||Recruiting|
|Lucerne, Luzern, Switzerland, 6000|
|Contact: Paul Erne, MD ++41 41 205 51 06 email@example.com|
|Contact: Christoph Auf der Maur, MD ++41 41 2005 51 48|
|Principal Investigator: Paul Erne, MD|
|Sub-Investigator: Christoph Auf der Maur, MD|
|Principal Investigator:||Paul Erne, MD||Luzerner Kantonsspital|