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Comparison of Transparent Retractable Extension Device and Narrow Band Imaging on Colorectal Adenoma Detection

This study has been completed.
Information provided by (Responsible Party):
Akira Horiuchi, Showa Inan General Hospital Identifier:
First received: October 1, 2008
Last updated: November 17, 2015
Last verified: November 2015
The investigators previously reported that colonoscopy with a transparent retractable extension (TRE) device improved the adenoma detection rate without affecting intubation and withdrawal times. On the other hand, colonoscopy using narrow band imaging (NBI) is expected to lead to higher rate s of adenoma detection. The investigators compared the effects of TRE device on colorectal adenoma detection with those of NBI.

Condition Intervention
Colorectal Cancer Screening
Device: TRE vs. NBI

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Single Blind (Investigator)
Primary Purpose: Diagnostic

Further study details as provided by Showa Inan General Hospital:

Primary Outcome Measures:
  • Colorectal adenoma detection rate [ Time Frame: after colonoscopy ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Procedure time, complication [ Time Frame: after colonoscopy ] [ Designated as safety issue: Yes ]

Enrollment: 200
Study Start Date: January 2007
Study Completion Date: December 2010
Primary Completion Date: December 2010 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: 2
The investigators evaluate beneficial effect of colonoscopy using narrow band imaging (NBI) for colorectal adenoma detection.
Device: TRE vs. NBI
Experimental: 1
The investigators evaluate the beneficial effect of colonoscopy with a transparent retractable extension (TRE) device on colorectal adenoma detection rate.
Device: TRE vs. NBI


Ages Eligible for Study:   20 Years to 100 Years   (Adult, Senior)
Genders Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Exclusion Criteria:

  • Age less than 20 years old
  • Pregnant
  • American Society of Anesthesiologists class III and IV
  • Overweight (body weight > 100 kg)
  • Allergic to the drugs used or its components (soybeans or eggs)
  • Poor bowel preparation
  • Previous colorectal surgical resection
  Contacts and Locations
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Please refer to this study by its identifier: NCT00765180

Showa Inan General hospital
Komagane, Nagano, Japan, 399-4191
Sponsors and Collaborators
Showa Inan General Hospital
  More Information

Responsible Party: Akira Horiuchi, Digestive Disease Center, Showa Inan General Hospital Identifier: NCT00765180     History of Changes
Other Study ID Numbers: TRE2 
Study First Received: October 1, 2008
Last Updated: November 17, 2015
Health Authority: Japan: Ministry of Health, Labor and Welfare

Keywords provided by Showa Inan General Hospital:

Additional relevant MeSH terms:
Colorectal Neoplasms
Intestinal Neoplasms
Gastrointestinal Neoplasms
Digestive System Neoplasms
Neoplasms by Site
Digestive System Diseases
Gastrointestinal Diseases
Colonic Diseases
Intestinal Diseases
Rectal Diseases processed this record on January 14, 2017