Skin Imaging With Technologies in Development

This study is currently recruiting participants. (see Contacts and Locations)
Verified February 2016 by University of California, Irvine
Sponsor:
Collaborator:
Beckman Laser Institute University of California Irvine
Information provided by (Responsible Party):
Beckman Laser Institute and Medical Center, University of California, Irvine
ClinicalTrials.gov Identifier:
NCT00764920
First received: September 30, 2008
Last updated: February 5, 2016
Last verified: February 2016
  Purpose
The purpose of this research is to develop non-invasive imaging modalities for assessment of skin. This is a pilot study which will use multiple imaging modalities to collect information on normal and lesional skin. The researchers understand that the purpose of this study is not to evaluate any particular treatment and an investigation of a new therapeutic intervention would require an additional protocol. Skin conditions to be studied include vascular lesions, pigmentary disorders, inflammatory conditions and neoplasms.

Condition Intervention
Pigmented Skin Lesion of Uncertain Nature
Device: non-invasive imaging modalities for assessment of skin

Study Type: Observational
Official Title: Non-invasive Imaging Modalities for Assessment of Normal and Lesional Skin

Resource links provided by NLM:


Further study details as provided by University of California, Irvine:

Primary Outcome Measures:
  • Collect information on normal and lesional skin [ Time Frame: up to 12 weeks ] [ Designated as safety issue: Yes ]
    Develop non-invasive imaging modalities for assessment of skin.


Estimated Enrollment: 350
Study Start Date: October 2008
Estimated Study Completion Date: October 2018
Estimated Primary Completion Date: October 2018 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
Skin Imaging
non-invasive imaging modalities for assessment of skin
Device: non-invasive imaging modalities for assessment of skin
skin imaging

Detailed Description:

Normal and lesional skin will be assessed by the following imaging modalities:

  1. Laser Speckle Imaging can provide information about relative blood flow in a tissue. In skin it can be used to determine what areas have more blood flow and whether a particular intervention or treatment affects blood flow.
  2. Optical Coherence Tomography and Optical Doppler Tomography can provide pictures of blood vessels in an area of the body and can also tell how fast blood is flowing in that area.
  3. Photon Migration Spectroscopy can provide information about the amount of blood, oxygen, fat and water is in a tissue.
  4. Multi-Spectral Imaging can provide a 3 dimensional image of structures within the skin.
  5. Multiphoton Microscopy can provide images of structures of the skin.
  Eligibility

Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Study population will be selected from University of California Irvine Medical Clinic
Criteria

Inclusion Criteria:

  • adult male or female 18 years of age or older

Exclusion Criteria:

  • Younger than 18 years old
  • pregnant woman
  • breast feeding
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00764920

Contacts
Contact: Montana Compton, RN 949-824-9265 mocomton@uci.edu

Locations
United States, California
Beckman Laser Institute Medical clinic Recruiting
Irvine, California, United States, 92612
Contact: Kristen Kelly, MD    949-824-7997    kmkelly@uci.edu   
Contact: Ata Sharif, MD, MBA    949-824-9265    sharifs@uci.edu   
Sub-Investigator: Bernard Choi, PhD         
Sub-Investigator: Rolf Saager, PhD         
Sub-Investigator: Bruce Yang, MS         
Sub-Investigator: Mihaela Balu, PhD         
Sub-Investigator: Brian Wong, MD         
Sub-Investigator: Ata Sharif, MD, MBA         
Sub-Investigator: Michael Phelan, PHD         
Sponsors and Collaborators
University of California, Irvine
Beckman Laser Institute University of California Irvine
Investigators
Principal Investigator: Kristen M Kelly, MD Beckman Laser Institute University of California Irvine
  More Information

Responsible Party: Beckman Laser Institute and Medical Center, Kristen Kelly, M.D.,Professor Departments of Dermatology and Surgery, University of California, Irvine
ClinicalTrials.gov Identifier: NCT00764920     History of Changes
Other Study ID Numbers: NIH/LAMMP-2008-6307 
Study First Received: September 30, 2008
Last Updated: February 5, 2016
Health Authority: United States: Institutional Review Board

Keywords provided by University of California, Irvine:
human skin

Additional relevant MeSH terms:
Pigmentation Disorders
Skin Diseases

ClinicalTrials.gov processed this record on July 21, 2016