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The Investigation of a Fluorescence/Elastic Scattering Spectroscopy (F-ESS) Device for Oral Tissue Characterization

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00764569
First Posted: October 2, 2008
Last Update Posted: February 10, 2017
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Collaborator:
Beckman Laser Institute University of California Irvine
Information provided by (Responsible Party):
Beckman Laser Institute and Medical Center, University of California, Irvine
  Purpose
The overall objective of this work is to identify changes in the optical properties of oral tissues to develop a non-invasive tool for the detection, diagnosis and screening of oral pathology so that treatment can be provided at the earliest possible time.

Condition Intervention
Other Lesions of Oral Mucosa Device: Fluorescence/Elastic Scattering Spectroscopy

Study Type: Observational
Study Design: Observational Model: Other
Time Perspective: Other
Official Title: a Non-invasive Device for the Detection, Diagnosis and Screening of Oral Pathology

Further study details as provided by Beckman Laser Institute and Medical Center, University of California, Irvine:

Primary Outcome Measures:
  • Diagnostic Tool [ Time Frame: 4 weeks ]
    Fluorescence/Elastic Scattering Spectroscopy Oral tissue measurement


Enrollment: 77
Study Start Date: November 2008
Study Completion Date: June 2011
Primary Completion Date: June 2011 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
Oral Tissue measurement
Fluorescence/Elastic Scattering Spectroscopy Oral tissue measurement
Device: Fluorescence/Elastic Scattering Spectroscopy
Fluorescence/Elastic Scattering Spectroscopy Oral tissue measurement

Detailed Description:
Specifically, we will be obtaining optical spectroscopic data using a fiber optic contact probe that exploits elastic-scattering spectroscopy and fluorescence spectroscopy. Both of these technique have independently shown to provide signatures for the onset of cancer, with varied success. The purpose of this effort is to combine the two techniques and develop and understanding of the signatures obtained in both normal and abnormal oral tissue with simultaneous collection of these optical signatures.
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
community sample
Criteria

Inclusion Criteria:

  • adult over 18 years of age

Exclusion Criteria:

  • younger than 18 years of age
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00764569


Locations
United States, California
Beckman Laser Institute Medical clinic
Irvine, California, United States, 92612
UCI student health center
Irvine, California, United States, 92612
Sponsors and Collaborators
University of California, Irvine
Beckman Laser Institute University of California Irvine
Investigators
Principal Investigator: Petra Wilder-Smith, DDS, PhD Beckman Laser Institute University of California Irvine
  More Information

Responsible Party: Beckman Laser Institute and Medical Center, Petra Wilder-Smith, DDS., PhD., Professor, Director of Dentistry, University of California, Irvine
ClinicalTrials.gov Identifier: NCT00764569     History of Changes
Other Study ID Numbers: NIH-DOD-LAMMP- 2008-6355
First Submitted: October 1, 2008
First Posted: October 2, 2008
Last Update Posted: February 10, 2017
Last Verified: February 2017

Keywords provided by Beckman Laser Institute and Medical Center, University of California, Irvine:
oral tissue