Treatment for Word Retrieval Impairments in Aphasia

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.

ClinicalTrials.gov Identifier: NCT00764400

Recruitment Status : Completed

First Posted : October 2, 2008

Last Update Posted : April 6, 2018

Sponsor:

Collaborator:

National Institute on Deafness and Other Communication Disorders (NIDCD)

Information provided by (Responsible Party):

Dr. Anastasia Raymer, Old Dominion University

Study Description

Brief Summary:

In this study the investigators are examining the effectiveness of two different speech therapy protocols for word retrieval impairments experienced by individuals with stroke-induced aphasia. One treatment involves errorless naming treatment and the other employs verbal plus gestural facilitation of word retrieval. Participants will receive one of the two treatments over several months. Before and after treatment the investigators will administer several tests and conversational samples to examine changes associated with the treatments. The investigators hypothesize that, whereas both treatments will lead to improvements in words rehearsed in therapy, communication outcomes in conversation will be broader for the verbal plus gestural protocol.

Condition or disease	Intervention/treatment	Phase
Stroke	Behavioral: Word Retrieval Treatments for Aphasia	Not Applicable

Detailed Description:

Study Design


Study Type :	Interventional (Clinical Trial)
Actual Enrollment :	24 participants
Allocation:	Randomized
Intervention Model:	Parallel Assignment
Masking:	Single (Investigator)
Primary Purpose:	Treatment
Official Title:	Communication Outcomes for Naming Treatments in Aphasia
Study Start Date :	August 2008
Actual Primary Completion Date :	June 2013
Actual Study Completion Date :	July 2013

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Aphasia Speech and Communication Disorders

U.S. FDA Resources

Arms and Interventions

Arm	Intervention/treatment
Experimental: Errorless Naming Treatment	Behavioral: Word Retrieval Treatments for Aphasia Speech therapy sessions take place 4 times per week for up to 90 minutes per session. Following a phase of baseline pre-testing, two phases of speech therapy will take place lasting up to 20 sessions per phase. Post-testing will take place immediately upon completion of the treatment phases and again at 1 month post study completion.
Experimental: Verbal+Gestural Facilitation	Behavioral: Word Retrieval Treatments for Aphasia Speech therapy sessions take place 4 times per week for up to 90 minutes per session. Following a phase of baseline pre-testing, two phases of speech therapy will take place lasting up to 20 sessions per phase. Post-testing will take place immediately upon completion of the treatment phases and again at 1 month post study completion.

Outcome Measures

Primary Outcome Measures :

Daily Probe Picture Naming [ Time Frame: daily probes from three times per week for up to 3 months and one month posttreatment ]

Secondary Outcome Measures :

Western Aphasia Battery [ Time Frame: pre-treatment and at treatment completion ]
Boston Naming Test [ Time Frame: pretreatment and at treatment completion ]
Discourse Sample [ Time Frame: pre-treatment and at treatment completion ]

Eligibility Criteria

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:	21 Years to 90 Years (Adult, Older Adult)
Sexes Eligible for Study:	All
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

left hemisphere stroke >4 months earlier
aphasia with word retrieval impairments
>21 years of age right handed
speaker of English as the preferred language
>6 grade education

Exclusion Criteria:

history of developmental learning difficulties
history of prior neurological illnesses
chronic medical illnesses that restrict participation in speech therapy
alcohol or drug dependence
severe uncorrected impairments of vision or hearing

Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00764400

Locations


United States, Virginia
Old Dominion University Speech and Hearing Clinic
Norfolk, Virginia, United States, 23529

Sponsors and Collaborators

Old Dominion University

National Institute on Deafness and Other Communication Disorders (NIDCD)

Investigators


Principal Investigator:	Anastasia M Raymer, PhD	Old Dominion University

More Information


Responsible Party:	Dr. Anastasia Raymer, Professor of Communications Disorders & Special Education, Old Dominion University
ClinicalTrials.gov Identifier:	NCT00764400 History of Changes
Other Study ID Numbers:	R15DC009690 ( U.S. NIH Grant/Contract ) 3R15DC009690 ( U.S. NIH Grant/Contract )
First Posted:	October 2, 2008 Key Record Dates
Last Update Posted:	April 6, 2018
Last Verified:	April 2018

Keywords provided by Dr. Anastasia Raymer, Old Dominion University:


aphasia anomia speech therapy rehabilitation

Additional relevant MeSH terms:


Aphasia Speech Disorders Language Disorders Communication Disorders	Neurobehavioral Manifestations Neurologic Manifestations Nervous System Diseases Signs and Symptoms

To Top