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Treatment for Word Retrieval Impairments in Aphasia

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified May 2012 by Dr. Anastasia Raymer, Old Dominion University.
Recruitment status was:  Recruiting
Sponsor:
ClinicalTrials.gov Identifier:
NCT00764400
First Posted: October 2, 2008
Last Update Posted: May 21, 2012
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Collaborator:
National Institute on Deafness and Other Communication Disorders (NIDCD)
Information provided by (Responsible Party):
Dr. Anastasia Raymer, Old Dominion University
  Purpose
In this study the investigators are examining the effectiveness of two different speech therapy protocols for word retrieval impairments experienced by individuals with stroke-induced aphasia. One treatment involves errorless naming treatment and the other employs verbal plus gestural facilitation of word retrieval. Participants will receive one of the two treatments over several months. Before and after treatment the investigators will administer several tests and conversational samples to examine changes associated with the treatments. The investigators hypothesize that, whereas both treatments will lead to improvements in words rehearsed in therapy, communication outcomes in conversation will be broader for the verbal plus gestural protocol.

Condition Intervention Phase
Stroke Behavioral: Word Retrieval Treatments for Aphasia Phase 1

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Investigator)
Primary Purpose: Treatment
Official Title: Communication Outcomes for Naming Treatments in Aphasia

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Dr. Anastasia Raymer, Old Dominion University:

Primary Outcome Measures:
  • Daily Probe Picture Naming [ Time Frame: daily probes from three times per week for up to 3 months and one month posttreatment ]

Secondary Outcome Measures:
  • Western Aphasia Battery [ Time Frame: pre-treatment and at treatment completion ]
  • Boston Naming Test [ Time Frame: pretreatment and at treatment completion ]
  • Discourse Sample [ Time Frame: pre-treatment and at treatment completion ]
Estimated Enrollment: 16
Study Start Date: August 2008
Estimated Study Completion Date: July 2012
Estimated Primary Completion Date: June 2012 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Errorless Naming Treatment Behavioral: Word Retrieval Treatments for Aphasia
Speech therapy sessions take place 4 times per week for up to 90 minutes per session. Following a phase of baseline pre-testing, two phases of speech therapy will take place lasting up to 20 sessions per phase. Post-testing will take place immediately upon completion of the treatment phases and again at 1 month post study completion.
Experimental: Verbal+Gestural Facilitation Behavioral: Word Retrieval Treatments for Aphasia
Speech therapy sessions take place 4 times per week for up to 90 minutes per session. Following a phase of baseline pre-testing, two phases of speech therapy will take place lasting up to 20 sessions per phase. Post-testing will take place immediately upon completion of the treatment phases and again at 1 month post study completion.

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   21 Years to 90 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • left hemisphere stroke >4 months earlier
  • aphasia with word retrieval impairments
  • >21 years of age right handed
  • speaker of English as the preferred language
  • >6 grade education

Exclusion Criteria:

  • history of developmental learning difficulties
  • history of prior neurological illnesses
  • chronic medical illnesses that restrict participation in speech therapy
  • alcohol or drug dependence
  • severe uncorrected impairments of vision or hearing
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00764400


Contacts
Contact: Anastasia M Raymer, PhD 757-683-4522 sraymer@odu.edu
Contact: Sheryl Spence 757-683-4117

Locations
United States, Virginia
Old Dominion University Speech and Hearing Clinic Recruiting
Norfolk, Virginia, United States, 23529
Contact: Anastasia M Raymer, PhD    757-683-4522    sraymer@odu.edu   
Principal Investigator: Anastasia Raymer, PhD         
Sponsors and Collaborators
Old Dominion University
National Institute on Deafness and Other Communication Disorders (NIDCD)
Investigators
Principal Investigator: Anastasia M Raymer, PhD Old Dominion University
  More Information

Responsible Party: Dr. Anastasia Raymer, Professor of Communications Disorders & Special Education, Old Dominion University
ClinicalTrials.gov Identifier: NCT00764400     History of Changes
Other Study ID Numbers: R15DC009690 ( U.S. NIH Grant/Contract )
3R15DC009690 ( U.S. NIH Grant/Contract )
First Submitted: September 30, 2008
First Posted: October 2, 2008
Last Update Posted: May 21, 2012
Last Verified: May 2012

Keywords provided by Dr. Anastasia Raymer, Old Dominion University:
aphasia
anomia
speech therapy
rehabilitation

Additional relevant MeSH terms:
Aphasia
Speech Disorders
Language Disorders
Communication Disorders
 Neurobehavioral Manifestations
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms