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Attentional Bias Modification in Patients With Posttraumatic Stress Disorder

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ClinicalTrials.gov Identifier: NCT00764101
Recruitment Status : Completed
First Posted : October 1, 2008
Last Update Posted : July 8, 2011
Sponsor:
Collaborators:
Leiden University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development
Information provided by:
PsyQ

Brief Summary:
Randomized, placebo-controlled trial of 9 sessions of computerized attentional bias training on attentional bias and on symptoms of Posttraumatic Stress Disorder.

Condition or disease Intervention/treatment Phase
Posttraumatic Stress Disorder Behavioral: Attentional Bias Modification Phase 2

Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 80 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Effects of Attentional Bias Modification on Attentional Bias and Symptoms of Posttraumatic Stress Disorder
Study Start Date : September 2008
Actual Primary Completion Date : April 2010
Actual Study Completion Date : April 2010

Resource links provided by the National Library of Medicine


Arm Intervention/treatment
Experimental: 1
9 sessions of attentional bias modification (computerized training program)
Behavioral: Attentional Bias Modification
computerized training to reduce attentional bias in posttraumatic stress disorder
Other Name: Attentional Training

Placebo Comparator: 2
Attentional control condition (placebo training program)
Behavioral: Attentional Bias Modification
computerized training to reduce attentional bias in posttraumatic stress disorder
Other Name: Attentional Training




Primary Outcome Measures :
  1. Clinician-Administered PTSD Scale (CAPS) [ Time Frame: End of Trial + 3 week Follow-Up ]

Secondary Outcome Measures :
  1. PTSD symptoms (self-report) [ Time Frame: end of trial + 3wk Follow Up ]
  2. Attentional Bias (dot-probe test) [ Time Frame: End of trial + 3wk Follow-up ]
  3. Emotional Stroop Interference [ Time Frame: End of trial + 3wk Follow Up ]


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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Diagnosis of Posttraumatic Stress Disorder

Exclusion Criteria:

  • Diagnosis of psychosis, drug- or alcohol dependency/abuse;
  • Unable to fill in questionnaires in Dutch;
  • Color blindness (Stroop test).

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00764101


Locations
Netherlands
PsyQ Haaglanden, department of psychotrauma
Den Haag, Zuid Holland, Netherlands, 2593 HR
Sponsors and Collaborators
PsyQ
Leiden University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development
Investigators
Study Director: Willem van der Does, professor Leiden University Medical Center
Principal Investigator: Maartje Schoorl, MS PsyQ Nederland bv

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Willem Van der Does, PhD, Leiden University
ClinicalTrials.gov Identifier: NCT00764101     History of Changes
Other Study ID Numbers: 60-60105-98-128
First Posted: October 1, 2008    Key Record Dates
Last Update Posted: July 8, 2011
Last Verified: July 2011

Additional relevant MeSH terms:
Disease
Stress Disorders, Traumatic
Stress Disorders, Post-Traumatic
Pathologic Processes
Trauma and Stressor Related Disorders
Mental Disorders