Observation of Change in Clinical Global Impression Scores in Schizophrenia Patients Receiving Seroquel XR Treatment

This study has been completed.
Information provided by:
ClinicalTrials.gov Identifier:
First received: September 23, 2008
Last updated: December 8, 2010
Last verified: December 2010

The purpose of this study is to assess severity of illness in schizophrenia patients in routine clinical practice at the time of entry in the study and after the treatment with Seroquel XR for 8 weeks.

PLEASE NOTE: Seroquel SR and Seroquel XR refer to the same formulation. The SR designation was changed to XR after consultation with FDA.


Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Observation of Change in Clinical Global Impression Scores in Schizophrenia Patients Receiving Seroquel XR Treatment

Resource links provided by NLM:

Further study details as provided by AstraZeneca:

Primary Outcome Measures:
  • Improvement in CGI scores and BPRS comparing visits 1 and 3. [ Time Frame: twice with 4 week interval ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • To evaluate compliance to therapy [ Time Frame: twice with 4 week interval ] [ Designated as safety issue: No ]

Estimated Enrollment: 80
Study Start Date: September 2008
Study Completion Date: March 2009
Primary Completion Date: March 2009 (Final data collection date for primary outcome measure)
Adult schizophrenia patients already on Seroquel XR therapy


Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
primary care clinics

Inclusion Criteria:

  • Adult patients with Schizophrenia prescribed on Seroquel XR according to the approved product information before inclusion in this non-interventional study
  • Signed and dated Patient Informed Consent (ICF)

Exclusion Criteria:

  • Hypersensitivity to the active substance or to any of the excipients of Seroquel XR
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00758251

Research Site
Bauska, Latvia
Research SIte
Cesis, Latvia
Research Site
Daugavpils, Latvia
Research Site
Dobele, Latvia
Research Site
Jekabpils, Latvia
Research Site
Jelgava, Latvia
Research Site
Jurmala, Latvia
Research Site
Kuldiga, Latvia
Research Site
Liepaja, Latvia
Research Site
Riga, Latvia
Research Site
Saldus, Latvia
Research Site
Strenci, Latvia
Research Site
Talsi, Latvia
Research Site
Tukums, Latvia
Research Site
Valmiera, Latvia
Sponsors and Collaborators
Study Director: Agrita Hartmane AstraZeneca Latvia
  More Information

No publications provided

Responsible Party: Janis Dobelis, Country Manager, AstraZeneca MC Latvia
ClinicalTrials.gov Identifier: NCT00758251     History of Changes
Other Study ID Numbers: NIS-NLV-SER-2008/1 
Study First Received: September 23, 2008
Last Updated: December 8, 2010
Health Authority: Latvia: State Agency of Medicines

Keywords provided by AstraZeneca:
Seroquel XR

Additional relevant MeSH terms:
Mental Disorders
Schizophrenia and Disorders with Psychotic Features
Antipsychotic Agents
Central Nervous System Agents
Central Nervous System Depressants
Pharmacologic Actions
Physiological Effects of Drugs
Psychotropic Drugs
Therapeutic Uses
Tranquilizing Agents

ClinicalTrials.gov processed this record on February 11, 2016