Obstructive Sleep Apnea Syndrome and Attention Executive Function Disturbances
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ClinicalTrials.gov Identifier: NCT00757796
Verified September 2008 by Assaf-Harofeh Medical Center. Recruitment status was: Not yet recruiting
Studies demonstrate that sleep disturbances are associated with cognitive dysfunction and attention deficit. However the correlation between the severity of obstructive sleep apnea and the degree of cognitive dysfunction was not demonstrated. Our hypothesis is that patients suffering from a more severe sleep apnea will demonstrate a greater degree of cognitive dysfunction.
Condition or disease
Obstructive Sleep Apnea
Studies demonstrate that sleep disturbances are associated with cognitive dysfunction and attention deficit. However the correlation between the severity of sleep disturbances and the degree of cognitive dysfunction was not demonstrated.We intend to study 80 patients with various degrees of obstructive sleep apnea. All patients will undergo executive cognitive tests as well as tests to assess for levels of depression, anxiety and attention.
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Ages Eligible for Study:
20 Years to 70 Years (Adult, Senior)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Patients aged 20 - 70 years with obstructive sleep apnea.
Apnea hypopnea index>5
Age 20 - 70 years
Known chronic cardiovascular or pulmonary disease
Patients s/p CVA or brain damage
Known depression or other psychiatric disorder
Patients with severe cognitive dysfunction (MMSE<25)
Patients receiving stimulants, antipsychotic or anti-depression medications