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Obstructive Sleep Apnea Syndrome and Attention Executive Function Disturbances

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ClinicalTrials.gov Identifier: NCT00757796
Recruitment Status : Unknown
Verified September 2008 by Assaf-Harofeh Medical Center.
Recruitment status was:  Not yet recruiting
First Posted : September 23, 2008
Last Update Posted : September 23, 2008
Sponsor:
Information provided by:
Assaf-Harofeh Medical Center

Brief Summary:
Studies demonstrate that sleep disturbances are associated with cognitive dysfunction and attention deficit. However the correlation between the severity of obstructive sleep apnea and the degree of cognitive dysfunction was not demonstrated. Our hypothesis is that patients suffering from a more severe sleep apnea will demonstrate a greater degree of cognitive dysfunction.

Condition or disease
Obstructive Sleep Apnea

Detailed Description:
Studies demonstrate that sleep disturbances are associated with cognitive dysfunction and attention deficit. However the correlation between the severity of sleep disturbances and the degree of cognitive dysfunction was not demonstrated.We intend to study 80 patients with various degrees of obstructive sleep apnea. All patients will undergo executive cognitive tests as well as tests to assess for levels of depression, anxiety and attention.

Study Type : Observational
Estimated Enrollment : 80 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Obstructive Sleep Apnea Syndrome and Attention Executive Function Disturbances
Study Start Date : October 2008

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Sleep Apnea





Information from the National Library of Medicine

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Ages Eligible for Study:   20 Years to 70 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Patients aged 20 - 70 years with obstructive sleep apnea.
Criteria

Inclusion Criteria:

  1. Apnea hypopnea index>5
  2. Age 20 - 70 years

Exclusion Criteria:

  1. Pregnant women
  2. Known chronic cardiovascular or pulmonary disease
  3. Patients s/p CVA or brain damage
  4. Known depression or other psychiatric disorder
  5. Patients with severe cognitive dysfunction (MMSE<25)
  6. Patients receiving stimulants, antipsychotic or anti-depression medications

Responsible Party: Itzhak Shpirer, The Sleep Laboratory, Assaf Harofeh Medical Center, Zerifin, Israel
ClinicalTrials.gov Identifier: NCT00757796     History of Changes
Other Study ID Numbers: 143/06
First Posted: September 23, 2008    Key Record Dates
Last Update Posted: September 23, 2008
Last Verified: September 2008

Additional relevant MeSH terms:
Apnea
Sleep Apnea Syndromes
Sleep Apnea, Obstructive
Respiration Disorders
Respiratory Tract Diseases
Signs and Symptoms, Respiratory
Signs and Symptoms
Sleep Disorders, Intrinsic
Dyssomnias
Sleep Wake Disorders
Nervous System Diseases