The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government.
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The purpose of this investigational study is to find out what hormones are present in healthy male testicles using fine needle aspiration.
Condition or disease
HealthyMale InfertilityProstate Disease
We will collect a very small amount of fluid from each testicle. Participation will last up to 12 weeks. The study involves a minimum of 4 visits, the screening visit and procedure Day, fine needle aspiration of the testes (about 1-1.5 hours each) and two follow-up visits (about 30-45 minutes). Over the course of the study, you will have a little less than a 1/3-cup of blood drawn (roughly 2-3 tablespoons at each visit).
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Ages Eligible for Study:
18 Years to 50 Years (Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
males between 18 and 50 years of age
sperm count greater than 20 million/ml, greater than 50% motility, and greater than 15% normal morphology
in good general health based on normal screening evaluation (consisting of a medical history, physical exam, normal sperm count, normal serum chemistry, hematology and baseline T, LH, and FSH levels)
body mass index ≥18 and ≤32 kg/m2
must agree not to participate in another research study involving drug exposure for the duration of the study
men in poor general health, with abnormal blood results
sperm counts <20 million/ml on two tests
chronic, ongoing alcohol or drug abuse
participation in a long-term male contraceptive study within the past three months
history of testicular or scrotal surgery
history of infertility
abnormal testicular exam
chronic pain syndrome
use of steroids, testosterone, or medications which might interfere with androgen metabolism including ketoconazole, glucocorticoids
known bleeding disorder
use of medications which may affect bleeding time (ongoing aspirin or anti-inflammatory use, coumadin)