Warfighter Head Injury Study
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT00754169|
Recruitment Status : Terminated
First Posted : September 17, 2008
Last Update Posted : October 6, 2017
This study will examine the long-term outcome of brain injuries, the effects of treatment on outcome and the effects of brain injury on people s behavior and abilities.
Men and women between 18 and 75 years of age who served in combat in the Iraq war may be eligible for this study. It will compare test results in those who sustained a traumatic penetrating or blast-related brain injury during combat with those who did not.
Participants undergo the following procedures over a 5-day period of testing that lasts about 6 hours a day:
- Medical history and physical examination.
- Blood test for genetic analysis.
- Electroencephalography (EEG) to measure the electrical activity of the brain.
- MRI or CT scans of the brain to look at the structure and blood flow of the brain.
- Functional near-infrared spectroscopy (fNIRS) to monitor blood flow in the front part of the brain blood by measuring changes in near-infrared light.
- Neuropsychological testing, including questionnaires, pen-and-paper or computerized tests, and performance of simple actions to measure brain function, language, memory and other cognitive abilities..
|Condition or disease|
|Study Type :||Observational|
|Actual Enrollment :||314 participants|
|Official Title:||Warfighter Head Injury Study a Comprehensive, Multidisciplinary Research Evaluation|
|Study Start Date :||September 5, 2008|
|Study Completion Date :||January 9, 2013|
- The effects of focal lesions on neuroplastic changes in cognitive and social functions following combat-related traumatic brain injury
- Genetic influence on neuroplastic changes in cognitive and social functions following combat-related traumatic brain injury
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00754169
|United States, Maryland|
|National Institutes of Health Clinical Center, 9000 Rockville Pike|
|Bethesda, Maryland, United States, 20892|
|Principal Investigator:||Eric M Wassermann, M.D.||National Institute of Neurological Disorders and Stroke (NINDS)|