We are updating the design of this site. Learn more.
Show more
ClinicalTrials.gov
ClinicalTrials.gov Menu

Urine Concentration of S100B in Extremely Premature Infants

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00747591
First Posted: September 5, 2008
Last Update Posted: July 23, 2010
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
University of Utah
  Purpose
S100B, a calcium-binding protein, is found predominantly in the central nervous system (CNS) and is increased in CSF and blood after CNS injury. There are two objectives to this study. Is urine S100B concentration correlated with the serum concentration of S100B in infants born at 29-36 weeks gestation. The presence and severity of intracranial pathology on S100B concentration will be investigated. Further analysis will demonstrate if birth weight, daily fluid intake, urine output, and urine creatinine influence this relationship.

Condition
Premature Infants

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Retrospective
Official Title: Correlation of Urine Concentration of S100B in Extremely Premature Infants With Gestational Age and Severity of Intraventricular Hemorrhage

Resource links provided by NLM:


Further study details as provided by University of Utah:

Enrollment: 68
Study Start Date: November 2002
Study Completion Date: April 2005
Primary Completion Date: February 2005 (Final data collection date for primary outcome measure)
  Show Detailed Description

  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   up to 7 Days   (Child)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Preterm infants born at <28 weeks gestation will be eligible for enrollment in this study.
Criteria

Inclusion Criteria:

  • Preterm infants born at <28 weeks gestation will be eligible for enrollment in this study.

Exclusion Criteria:

  • Infants with fetal malformations, chromosomal anomalies, and clinically significant sepsis (retractable hypotension, neutropenia, and thrombocytopenia) will be excluded, other.
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00747591


Locations
United States, Utah
University of Utah
Salt Lake City, Utah, United States, 84132
Sponsors and Collaborators
University of Utah
Investigators
Principal Investigator: Joanna Beachy, M.D. University of Utah
  More Information

Responsible Party: Joanna Beachy Ph.D., M.D., University of Utah Neonatology
ClinicalTrials.gov Identifier: NCT00747591     History of Changes
Other Study ID Numbers: 10870
First Submitted: September 3, 2008
First Posted: September 5, 2008
Last Update Posted: July 23, 2010
Last Verified: July 2010

Keywords provided by University of Utah:
urine
concentration
of S100B

Additional relevant MeSH terms:
Premature Birth
Obstetric Labor, Premature
Obstetric Labor Complications
Pregnancy Complications