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Effects of Atorvastatin on Adiponectin Levels and Insulin Sensitivity In Hypercholesterolemic Patients

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ClinicalTrials.gov Identifier: NCT00745836
Recruitment Status : Completed
First Posted : September 3, 2008
Last Update Posted : September 3, 2008
Sponsor:
Information provided by:
Gachon University Gil Medical Center

Brief Summary:
High dose atorvastatin may worsen insulin sensitivity.

Condition or disease Intervention/treatment Phase
Hypercholesterolemia Drug: statin Phase 4

Study Type : Interventional  (Clinical Trial)
Intervention Model: Parallel Assignment
Primary Purpose: Treatment
Study Start Date : January 2005
Actual Study Completion Date : August 2008

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Arm Intervention/treatment
Experimental: atorvastatin 10 mg, 80 mg Drug: statin




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Ages Eligible for Study:   25 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • hypercholesterolemia

Exclusion Criteria:

  • chronic renal disease

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00745836


Locations
Korea, Republic of
Gil Medical Center
Incheon, Korea, Republic of, 405760
Sponsors and Collaborators
Gachon University Gil Medical Center

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
ClinicalTrials.gov Identifier: NCT00745836     History of Changes
Other Study ID Numbers: GMC-200508
First Posted: September 3, 2008    Key Record Dates
Last Update Posted: September 3, 2008
Last Verified: September 2008

Keywords provided by Gachon University Gil Medical Center:
insulin sensitivity

Additional relevant MeSH terms:
Hypercholesterolemia
Insulin Resistance
Hyperlipidemias
Dyslipidemias
Lipid Metabolism Disorders
Metabolic Diseases
Hyperinsulinism
Glucose Metabolism Disorders
Atorvastatin Calcium
Insulin
Anticholesteremic Agents
Hypolipidemic Agents
Antimetabolites
Molecular Mechanisms of Pharmacological Action
Lipid Regulating Agents
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Enzyme Inhibitors
Hypoglycemic Agents
Physiological Effects of Drugs