Screening for Attention-deficit/Hyperactivity Disorder (ADHD) in Adolescent and Adult High Risk Populations

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00745524
Recruitment Status : Completed
First Posted : September 3, 2008
Last Update Posted : May 17, 2012
Information provided by (Responsible Party):
National Taiwan University Hospital

Brief Summary:
This study aims to investigate the prevalence of ADHD and other psychopathology, and current function and life quality among several high risk populations of imprisoned adults and adolescents who receive special resources in school or dropout from school.

Condition or disease
Attention Deficit Disorder With Hyperactivity

Detailed Description:

Attention-deficit/hyperactivity disorder (ADHD) is a common (5-10%) childhood-onset neuropsychiatric disorder worldwide among children and adolescents with 50- 60% persistence to adulthood (3-4%). Individuals with ADHD have been reported to have higher risk of school failure, conduct problems, antisocial behaviors, legal problems, substance use problems and other psychiatric comorbidities, and face many difficulties of the interpersonal relationship, occupation and family in every day life. Despite plenty of researches reported in the west countries, we have limited information in Taiwan about adult ADHD and the associated impact on the function and quality of life of the affected individuals. For the perspective of public health, it's mandatory to collect information from the high risk populations of ADHD for further policy establishment to prevent further impact on individuals, families, and society in Taiwan.

This study target on two populations: (1) imprisoned adults (2) adolescents with problems in school and followed by three private charitable organizations. Each population is assessed by the instruments for ADHD symptoms (ASRS and SNAP-IV), psychopathology (ASRI and/or YSR and CBCL), and academic/social/occupational /family function (WFIRS-S, WFIRS-P). Adult population is also checked for the quality of life (AAQoL). We will recruit the community-based controls matching with sex and age is assessed with the same instruments.

We anticipate that this study will provide the primitive data on the prevalence of ADHD and other psychopathology, academic/occupational/social/family function, quality of life of adolescent and adult patients in the high risk populations, will evaluate the difference between adults in prison, adolescents dropping out from school, and their community controls with regards to symptomatology, quality of life, and function; and young psychiatric researchers will learn to collect data, conduct statistical analysis, and prepare the manuscript. Our findings should have clinical implication in assessing adults and adolescents at high risk of ADHD and provide the reference data for future public health policy planning regarding early identification of ADHD at childhood and intervention program to offset the adverse social and academic/occupational sequalae of ADHD.

Study Type : Observational
Actual Enrollment : 1910 participants
Observational Model: Case Control
Official Title: Screening for Attention-deficit/Hyperactivity Disorder (ADHD) in Adolescent and Adult High Risk Populations
Study Start Date : February 2008
Actual Study Completion Date : December 2009

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Information from the National Library of Medicine

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Ages Eligible for Study:   13 Years to 65 Years   (Child, Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Imprisoned adults; adolescents with problems in school and followed by three private charitable organizations; community sample

Inclusion Criteria:

  • The adult subjects aged 20~65 form National Tainan Prison are recruited.
  • The adolescent subjects aged 13~19, drop out from school or receiving special services, followed by three private charitable organizations are recruited.
  • The controls will be recruited according to the structure of sex and age of the cases.

Exclusion Criteria:

  • In the major depressive episode, comorbid with severe anxiety disorders or during substance intoxication or withdrawal, or during the acute psychotic episode at the time of evaluation.
  • With neurodegenerative disorder, epilepsy, involuntary movement disorder, congenital metabolic disorder, brain tumor, history of severe head trauma, and history of craniotomy.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00745524

National Tainan Prison
Tainan, Taiwan, 71150
Tainan Family Educational Center
Tainan, Taiwan, 730
Sponsors and Collaborators
National Taiwan University Hospital
Principal Investigator: Susan Shur-Fen Gau, MD, PhD National Taiwan University Hospital

Responsible Party: National Taiwan University Hospital Identifier: NCT00745524     History of Changes
Other Study ID Numbers: 200801026R
First Posted: September 3, 2008    Key Record Dates
Last Update Posted: May 17, 2012
Last Verified: April 2012

Keywords provided by National Taiwan University Hospital:
Attention-deficit hyperactivity disorder
high risk population
functional impairment
quality of life

Additional relevant MeSH terms:
Attention Deficit Disorder with Hyperactivity
Pathologic Processes
Attention Deficit and Disruptive Behavior Disorders
Neurodevelopmental Disorders
Mental Disorders
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms