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Additive Beneficial Effects of Atorvastatin Combined With Amlodipine In Treatment of Hypertension

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00741078
First Posted: August 26, 2008
Last Update Posted: August 29, 2008
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
Gachon University Gil Medical Center
  Purpose
The investigators hypothesized combination therapy would be superior to monotherapy.

Condition Intervention Phase
Hypertension Drug: statin, amlodipine Phase 4

Study Type: Interventional
Study Design: Intervention Model: Crossover Assignment
Primary Purpose: Treatment
Official Title: Additive Beneficial Effects of Atorvastatin Combined With Amlodipine In Treatment of Hypertension

Resource links provided by NLM:


Further study details as provided by Gachon University Gil Medical Center:

Study Start Date: December 2004
Study Completion Date: August 2008
Arms Assigned Interventions
Experimental: atorvastatin, amlodipine Drug: statin, amlodipine

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   25 Years to 75 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Hypertension

Exclusion Criteria:

  • Chronic renal disease
  • Severe hypertension
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00741078


Locations
Korea, Republic of
Gil Medical Center
Incheon, Korea, Republic of, 405-760
Sponsors and Collaborators
Gachon University Gil Medical Center
  More Information

ClinicalTrials.gov Identifier: NCT00741078     History of Changes
Other Study ID Numbers: GMC-200504
First Submitted: August 20, 2008
First Posted: August 26, 2008
Last Update Posted: August 29, 2008
Last Verified: August 2008

Keywords provided by Gachon University Gil Medical Center:
endothelial
function
insulin
sensitivity

Additional relevant MeSH terms:
Hypertension
Vascular Diseases
Cardiovascular Diseases
Atorvastatin Calcium
Amlodipine
Anticholesteremic Agents
Hypolipidemic Agents
Antimetabolites
Molecular Mechanisms of Pharmacological Action
Lipid Regulating Agents
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Enzyme Inhibitors
Antihypertensive Agents
Calcium Channel Blockers
Membrane Transport Modulators
Vasodilator Agents