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Physical Activity in Youth: Implications for Reversing Risk Factors for Type 2 Diabetes

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00739180
First Posted: August 21, 2008
Last Update Posted: November 6, 2012
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Collaborator:
American Diabetes Association
Information provided by (Responsible Party):
SoJung Lee, University of Pittsburgh
  Purpose
In this randomized controlled trial, we will examine the effect of a 3-month exercise training (aerobic exercise versus resistance exercise) without calorie restriction on total and regional adiposity, and risk of type 2 diabetes in overweight children and adolescents.

Condition Intervention
Abdominal Obesity Other: Control Other: Resistance Exercise Other: Aerobic exercise

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Physical Activity in Youth: Implications for Reversing Risk Factors for Type 2 Diabetes

Resource links provided by NLM:


Further study details as provided by SoJung Lee, University of Pittsburgh:

Primary Outcome Measures:
  • Abdominal obesity, visceral fat [ Time Frame: 3 month ]

Secondary Outcome Measures:
  • Insulin sensitivity and secretion, glucose tolerance [ Time Frame: 3 month ]

Enrollment: 45
Study Start Date: November 2007
Study Completion Date: October 2011
Primary Completion Date: October 2011 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Control
Standard care control
Other: Control
Standard care control (no exercise)
Active Comparator: Aerobic Exercise Other: Aerobic exercise
Supervised aerobic exercise using treadmills, bikes, and ellipticals
Active Comparator: Resistance Exercise Other: Resistance Exercise
Supervised resistance exercise using stack weight equipments.

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   12 Years to 18 Years   (Child, Adult)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Healthy overweight (BMI >-95th) youth between 12 and 18 years of age
  • Waist circumference >-75th percentile
  • Sedentary (no structured exercise >2 times/week for past 6 months)
  • Non-smokers, non-diabetic, no medical conditions
  • Weight stable for past 3 months

Exclusion Criteria:

  • Smokers,
  • diabetic,
  • psychiatric disorders,
  • syndromatic obesity
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00739180


Locations
United States, Pennsylvania
Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine
Pittsburgh, Pennsylvania, United States, 15213
Sponsors and Collaborators
University of Pittsburgh
American Diabetes Association
Investigators
Principal Investigator: SoJung Lee, PhD University of Pittsburgh
  More Information

Responsible Party: SoJung Lee, Assistant Professor of Pediatrics, University of Pittsburgh
ClinicalTrials.gov Identifier: NCT00739180     History of Changes
Other Study ID Numbers: 7-08-JF-27
First Submitted: August 20, 2008
First Posted: August 21, 2008
Last Update Posted: November 6, 2012
Last Verified: October 2012

Keywords provided by SoJung Lee, University of Pittsburgh:
Childhood obesity
Abdominal obesity
Visceral fat
Insulin resistance
Liver fat
Skeletal muscle lipid
Fitness

Additional relevant MeSH terms:
Obesity
Obesity, Abdominal
Overnutrition
Nutrition Disorders
Overweight
Body Weight
Signs and Symptoms