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In Vitro Fertilization (IVF) and Acupuncture for Infertility

This study has been terminated.
(Adjustments to ensure clear outcomes and scientific merit integrated. Study closed at 14 subjects. New protocol submitted to IRB.)
Information provided by (Responsible Party):
Pacific Fertility Center Identifier:
First received: August 13, 2008
Last updated: October 27, 2015
Last verified: October 2015
The aim of this investigation is to determine the value of combining acupuncture with infertility patients undergoing In Vitro Fertilization (IVF). The investigators will measure the outcomes of endometrial lining, uterine blood flow, hormones, stress levels, and pregnancy and live birth rates.

Condition Intervention
Infertility Procedure: acupuncture Procedure: IVF

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Outcomes Assessor)
Primary Purpose: Treatment
Official Title: IVF and Acupuncture for Infertility: A Randomized Controlled Trail

Resource links provided by NLM:

Further study details as provided by Pacific Fertility Center:

Primary Outcome Measures:
  • pregnancy [ Time Frame: week 10 of study ]

Secondary Outcome Measures:
  • uterine blood flow [ Time Frame: final measurement in week 8 ]

Enrollment: 320
Study Start Date: August 2008
Study Completion Date: October 2010
Primary Completion Date: October 2010 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: 1
Procedure: IVF
one 4 week IVF cycle
Procedure: acupuncture
16 treatments over 8 weeks


Ages Eligible for Study:   21 Years to 42 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • females between 21 and 42 years old
  • primary or secondary infertility
  • no more than 2 previously failed IVF cycles
  • undergoing IVF
  • FSH < 11

Exclusion Criteria:

  • FSH > 11
  • using an egg donor
  • using PGD
  • using heparin or lovanox protocols
  • estradiol level less than 20 or over 80
  • taking herbal therapy
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00736411

United States, California
Pacific Fertility Center
San Francisco, California, United States, 94133
Sponsors and Collaborators
Pacific Fertility Center
Study Director: Caylie J See, L.Ac. Pacific Fertility Center
  More Information

Responsible Party: Pacific Fertility Center Identifier: NCT00736411     History of Changes
Other Study ID Numbers: 28.005-2
Study First Received: August 13, 2008
Last Updated: October 27, 2015

Keywords provided by Pacific Fertility Center:

Additional relevant MeSH terms:
Genital Diseases, Male
Genital Diseases, Female processed this record on September 21, 2017