In Vitro Fertilization (IVF) and Acupuncture for Infertility

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00736411
Recruitment Status : Terminated (Adjustments to ensure clear outcomes and scientific merit integrated. Study closed at 14 subjects. New protocol submitted to IRB.)
First Posted : August 15, 2008
Last Update Posted : October 29, 2015
Information provided by (Responsible Party):
Pacific Fertility Center

Brief Summary:
The aim of this investigation is to determine the value of combining acupuncture with infertility patients undergoing In Vitro Fertilization (IVF). The investigators will measure the outcomes of endometrial lining, uterine blood flow, hormones, stress levels, and pregnancy and live birth rates.

Condition or disease Intervention/treatment Phase
Infertility Procedure: acupuncture Procedure: IVF Not Applicable

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 320 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Outcomes Assessor)
Primary Purpose: Treatment
Official Title: IVF and Acupuncture for Infertility: A Randomized Controlled Trail
Study Start Date : August 2008
Actual Primary Completion Date : October 2010
Actual Study Completion Date : October 2010

Resource links provided by the National Library of Medicine

Arm Intervention/treatment
Active Comparator: 1
Procedure: IVF
one 4 week IVF cycle

Procedure: acupuncture
16 treatments over 8 weeks

Primary Outcome Measures :
  1. pregnancy [ Time Frame: week 10 of study ]

Secondary Outcome Measures :
  1. uterine blood flow [ Time Frame: final measurement in week 8 ]

Information from the National Library of Medicine

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Ages Eligible for Study:   21 Years to 42 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • females between 21 and 42 years old
  • primary or secondary infertility
  • no more than 2 previously failed IVF cycles
  • undergoing IVF
  • FSH < 11

Exclusion Criteria:

  • FSH > 11
  • using an egg donor
  • using PGD
  • using heparin or lovanox protocols
  • estradiol level less than 20 or over 80
  • taking herbal therapy

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00736411

United States, California
Pacific Fertility Center
San Francisco, California, United States, 94133
Sponsors and Collaborators
Pacific Fertility Center
Study Director: Caylie J See, L.Ac. Pacific Fertility Center

Responsible Party: Pacific Fertility Center Identifier: NCT00736411     History of Changes
Other Study ID Numbers: 28.005-2
First Posted: August 15, 2008    Key Record Dates
Last Update Posted: October 29, 2015
Last Verified: October 2015

Keywords provided by Pacific Fertility Center:

Additional relevant MeSH terms:
Genital Diseases, Male
Genital Diseases, Female