Interval Training in Young Healthy Individuals
Individuals who participate in regular physical exercise possess a lower prevalence of cardiovascular risk factors such as hypertension, type 2 diabetes, obesity and hypercholesterolemia, and aerobic exercise is therefore considered an important adjuvant therapy in risk factor modification and to promote health.
The main focus of the present study is therefore to detect how rapid it is possible to increase aerobic capacity with interval running exercise.
The hypothesis is that it is possible to improve maximal oxygen uptake faster when increasing training frequency. The total gain in maximal oxygen uptake will however be the same between the two groups when they have performed the same amount of training
|Healthy Subjects Exercise Test||Behavioral: High frequency training Behavioral: normal frequence training|
|Study Design:||Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:||Interval Training: Training, Detraining and Retraining; an Interventional Study|
- Oxygen uptake [ Time Frame: Before and after the training-, detraining- and retraining-phase ]
- Cardiac function and skeletal muscle enzyme activity [ Time Frame: After training, detraining and retraining ]
|Study Start Date:||September 2008|
|Study Completion Date:||December 2009|
|Primary Completion Date:||June 2009 (Final data collection date for primary outcome measure)|
Experimental: High frequency training
24 interval exercises performed 8 times per week
Behavioral: High frequency training
24 training sessions, 8x weekly, followed by detraining phase 8 weeks, and retraining
Experimental: Normal frequency training
24 interval exercises performed 3 times per week
Behavioral: normal frequence training
24 training sessions, 3x weekly, followed by detraining phase 8 weeks, and retraining
We will perform aerobic interval training at an intensity of 90-95% of maximum heart rate in healthy individuals. The subjects will be randomly assigned to carry out a total of 24 exercise-sessions, either at 3 times per week or 8 times per week.
The two groups will carry out 24 training sessions before 8 weeks of detraining will provide how rapidly aerobic capacity is lost due to inactivity. After the detraining period a retraining phase is introduced to detect if improvements in aerobic capacity occur more rapidly compared to before the first training period
The subjects will be tested for oxygen uptake, pumping capacity of the heart, blood volume, skeletal muscle enzyme activity, endothelial function.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00733941
|Norwegian University of Science and Technology|
|Trondheim, Norway, 7020|
|Trondheim, Norway, 7489|
|Principal Investigator:||Øivind Rognmo, PhD||Norwegian University of Science and Technology|
|Principal Investigator:||Ulrik Wisløff, Professor||NTNU|