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Interval Training in Young Healthy Individuals

This study has been completed.
Information provided by (Responsible Party):
Norwegian University of Science and Technology Identifier:
First received: August 12, 2008
Last updated: May 26, 2015
Last verified: May 2015

Individuals who participate in regular physical exercise possess a lower prevalence of cardiovascular risk factors such as hypertension, type 2 diabetes, obesity and hypercholesterolemia, and aerobic exercise is therefore considered an important adjuvant therapy in risk factor modification and to promote health.

The main focus of the present study is therefore to detect how rapid it is possible to increase aerobic capacity with interval running exercise.

The hypothesis is that it is possible to improve maximal oxygen uptake faster when increasing training frequency. The total gain in maximal oxygen uptake will however be the same between the two groups when they have performed the same amount of training

Condition Intervention
Healthy Subjects
Exercise Test
Behavioral: High frequency training
Behavioral: normal frequence training

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Interval Training: Training, Detraining and Retraining; an Interventional Study

Resource links provided by NLM:

Further study details as provided by Norwegian University of Science and Technology:

Primary Outcome Measures:
  • Oxygen uptake [ Time Frame: Before and after the training-, detraining- and retraining-phase ]

Secondary Outcome Measures:
  • Cardiac function and skeletal muscle enzyme activity [ Time Frame: After training, detraining and retraining ]

Enrollment: 24
Study Start Date: September 2008
Study Completion Date: December 2009
Primary Completion Date: June 2009 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: High frequency training
24 interval exercises performed 8 times per week
Behavioral: High frequency training
24 training sessions, 8x weekly, followed by detraining phase 8 weeks, and retraining
Experimental: Normal frequency training
24 interval exercises performed 3 times per week
Behavioral: normal frequence training
24 training sessions, 3x weekly, followed by detraining phase 8 weeks, and retraining

Detailed Description:

We will perform aerobic interval training at an intensity of 90-95% of maximum heart rate in healthy individuals. The subjects will be randomly assigned to carry out a total of 24 exercise-sessions, either at 3 times per week or 8 times per week.

The two groups will carry out 24 training sessions before 8 weeks of detraining will provide how rapidly aerobic capacity is lost due to inactivity. After the detraining period a retraining phase is introduced to detect if improvements in aerobic capacity occur more rapidly compared to before the first training period

The subjects will be tested for oxygen uptake, pumping capacity of the heart, blood volume, skeletal muscle enzyme activity, endothelial function.


Ages Eligible for Study:   18 Years to 27 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • BMI<27, non-smokers, train less that 1-2 times per week, VO2max <60 for male and <50 for female.

Exclusion Criteria:

  • Hypertension, diabetes and cardiovascular disease.
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Please refer to this study by its identifier: NCT00733941

Norwegian University of Science and Technology
Trondheim, Norway, 7020
Trondheim, Norway, 7489
Sponsors and Collaborators
Norwegian University of Science and Technology
Principal Investigator: Øivind Rognmo, PhD Norwegian University of Science and Technology
Principal Investigator: Ulrik Wisløff, Professor NTNU
  More Information

Responsible Party: Norwegian University of Science and Technology Identifier: NCT00733941     History of Changes
Other Study ID Numbers: 4.2008.1755
Study First Received: August 12, 2008
Last Updated: May 26, 2015

Keywords provided by Norwegian University of Science and Technology:
Exercise test
Arterial diameter
Monitoring, physiologic
Oxygen Consumption processed this record on April 27, 2017