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Interval Training in Young Healthy Individuals

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00733941
First Posted: August 13, 2008
Last Update Posted: May 27, 2015
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Norwegian University of Science and Technology
  Purpose

Individuals who participate in regular physical exercise possess a lower prevalence of cardiovascular risk factors such as hypertension, type 2 diabetes, obesity and hypercholesterolemia, and aerobic exercise is therefore considered an important adjuvant therapy in risk factor modification and to promote health.

The main focus of the present study is therefore to detect how rapid it is possible to increase aerobic capacity with interval running exercise.

The hypothesis is that it is possible to improve maximal oxygen uptake faster when increasing training frequency. The total gain in maximal oxygen uptake will however be the same between the two groups when they have performed the same amount of training


Condition Intervention
Healthy Subjects Exercise Test Behavioral: High frequency training Behavioral: normal frequence training

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Interval Training: Training, Detraining and Retraining; an Interventional Study

Resource links provided by NLM:


Further study details as provided by Norwegian University of Science and Technology:

Primary Outcome Measures:
  • Oxygen uptake [ Time Frame: Before and after the training-, detraining- and retraining-phase ]

Secondary Outcome Measures:
  • Cardiac function and skeletal muscle enzyme activity [ Time Frame: After training, detraining and retraining ]

Enrollment: 24
Study Start Date: September 2008
Study Completion Date: December 2009
Primary Completion Date: June 2009 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: High frequency training
24 interval exercises performed 8 times per week
Behavioral: High frequency training
24 training sessions, 8x weekly, followed by detraining phase 8 weeks, and retraining
Experimental: Normal frequency training
24 interval exercises performed 3 times per week
Behavioral: normal frequence training
24 training sessions, 3x weekly, followed by detraining phase 8 weeks, and retraining

Detailed Description:

We will perform aerobic interval training at an intensity of 90-95% of maximum heart rate in healthy individuals. The subjects will be randomly assigned to carry out a total of 24 exercise-sessions, either at 3 times per week or 8 times per week.

The two groups will carry out 24 training sessions before 8 weeks of detraining will provide how rapidly aerobic capacity is lost due to inactivity. After the detraining period a retraining phase is introduced to detect if improvements in aerobic capacity occur more rapidly compared to before the first training period

The subjects will be tested for oxygen uptake, pumping capacity of the heart, blood volume, skeletal muscle enzyme activity, endothelial function.

  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years to 27 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • BMI<27, non-smokers, train less that 1-2 times per week, VO2max <60 for male and <50 for female.

Exclusion Criteria:

  • Hypertension, diabetes and cardiovascular disease.
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00733941


Locations
Norway
Norwegian University of Science and Technology
Trondheim, Norway, 7020
NTNU
Trondheim, Norway, 7489
Sponsors and Collaborators
Norwegian University of Science and Technology
Investigators
Principal Investigator: Øivind Rognmo, PhD Norwegian University of Science and Technology
Principal Investigator: Ulrik Wisløff, Professor NTNU
  More Information

Publications:
Responsible Party: Norwegian University of Science and Technology
ClinicalTrials.gov Identifier: NCT00733941     History of Changes
Other Study ID Numbers: 4.2008.1755
First Submitted: August 12, 2008
First Posted: August 13, 2008
Last Update Posted: May 27, 2015
Last Verified: May 2015

Keywords provided by Norwegian University of Science and Technology:
Exercise test
Running
Arterial diameter
Monitoring, physiologic
Oxygen Consumption