Prospective Comparison of Cirrus Versus Stratus Ocular Coherence Tomography for Different Retinal Pathology.

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00731458
Recruitment Status : Completed
First Posted : August 11, 2008
Last Update Posted : September 5, 2013
Research to Prevent Blindness
Information provided by (Responsible Party):
University of Chicago

Brief Summary:
Ocular Coherence Tomography (OCT) is a non-invasive ophthalmologic test that uses reflected, unheated, non-concentrated visible light in order to scan and provide a 2-dimensional topographic analysis of the retina and optic nerve. It has wide diagnostic utility especially in patients with clinically significant macular edema, glaucoma, and other retinal eye diseases. At the University of Chicago, we have utilized the Stratus brand OCT (Carl Zeiss Inc) for the past 5 years. Recently we have acquired a beta version of the company's new model, the Cirrus HD-OCT (Carl Zeiss Inc.) which features improved resolution, shorter scanning time and a more user-friendly interface. The purpose of this study is to compare findings between the two models in patients with different common and uncommon eye diseases, including diabetic macular edema, glaucoma and age-related macular degeneration. We hypothesis that the Cirrus OCT is able to accurately quantify eye pathology compared to Stratus OCT.

Condition or disease Intervention/treatment Phase
Retinal Pathology Device: Optical coherance tomography ( Cirrus; Stratus) Not Applicable

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 60 participants
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Health Services Research
Official Title: Prospective Comparison of Cirrus and Stratus Optical Coherence Tomography for Quantifying Retinal Thickness
Study Start Date : May 2007
Actual Primary Completion Date : November 2007
Actual Study Completion Date : November 2007

Intervention Details:
    Device: Optical coherance tomography ( Cirrus; Stratus)
    Non-contact retinal thickness analyzer
    Other Name: OCT; Cirrus; Stratus

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Any eye pathology that may cause macular edema.

Exclusion Criteria:

  • Vitreous media opacities including dense cataracts, vitreous hemorrhage, and corneal opacities

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00731458

Sponsors and Collaborators
University of Chicago
Research to Prevent Blindness
Principal Investigator: Seenu Hariprasad, M.D. University of Chicago