Association Study of Gene Polymorphisms With Cardiac Performance
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ClinicalTrials.gov Identifier: NCT00730899
Verified August 2008 by University Hospital, Essen. Recruitment status was: Recruiting
G Protein pathways plays a pivotal role in mediating positive inotropy and cardiac hypertrophy by transducing signals of neurohormones in cardiomyocytes. Single nucleotide polymorphisms (SNPs) in the G protein subunits Galphas and Galphaq have been shown to result in altered protein expression. We now want to examine whether G Protein polymorphisms alter NYHA functional class, and hemodynamic variables in patients with coronary artery disease scheduled for coronary artery bypass grafting .
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Ages Eligible for Study:
18 Years to 80 Years (Adult, Senior)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Patients with coronary artery disease scheduled for coronary artery bypass grafting in the university hospital
clinical diagnosis of coronary artery disease
patients scheduled for coronary artery bypass grafting