Refinement and Assessment of New MRI Technologies for Thoracic/ Cardiovascular Exams
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|ClinicalTrials.gov Identifier: NCT00727792|
Recruitment Status : Enrolling by invitation
First Posted : August 4, 2008
Last Update Posted : January 24, 2018
|Condition or disease||Intervention/treatment||Phase|
|Magnetic Resonance Imaging (MRI) of the Chest||Procedure: MRI -Clinical Procedure: MRI-Research||Not Applicable|
We will recruit patients to participate in the assessment of new MRI technologies designed to improve chest MRI exams that will result in improvements in patient care.
Several different MRI technologies will be evaluated. Specific evaluation of distinct technologies (eg. new head coil design, and new imaging sequence for the spine) may be evaluated simultaneously, or over non-overlapping periods in time.
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||100 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Primary Purpose:||Basic Science|
|Official Title:||Refinement and Assessment of New MRI Technologies for Thoracic/ Cardiovascular Exams|
|Study Start Date :||January 2009|
|Estimated Primary Completion Date :||December 2019|
|Estimated Study Completion Date :||December 2019|
Experimental: Group 2 - Research MRI
Subjects will have additional sequences and/or modification to MRI sequences.
MRI includes extra sequences
Active Comparator: Group 1 - Clinical MRI
Clinically ordered MRI scan. Subjects will not have any additional sequences or modifications to their clinically ordered MRI
Procedure: MRI -Clinical
MRI done is standard of care
- New MRI Technologies [ Time Frame: 3 years ]
Assessment of the new technologies will be quantified by a variety of performance and image quality/content measures. The appropriate set of measures will be selected based on specific features offered by each assessed technology, but will be drawn from the following quantities:
- Scan speed: Scan speed is time required to set-up and run the new technique relative to the standard method.
- Signal to noise: SNR (signal to noise ratio)is the ratio of average image intensity in target tissue relative to standard deviation of background areas (outside of body). This is a fundamental parameter used to quantify relative performance of new imaging sequences/hardware/software.
- Contrast to noise: CNR (contrast to noise)is the difference in average image intensity between two target tissues relative to noise. This is a key descriptor to quantity lesion/tissue conspicuity, thus is used to characterize relative performance of new imaging sequence/hardware/software.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00727792
|United States, Michigan|
|University of Michigan Hospital|
|Ann Arbor, Michigan, United States, 48109|
|Principal Investigator:||Jadranka Stojanovska, MD||University of Michigan|