A Yoga and Wellness Program for Breast Cancer Survivors With Persistent Fatigue
This randomized controlled trial will compare the effectiveness of an Iyengar Yoga intervention to a Wellness Seminar health education lecture series, for improvements in energy, mood and biological functioning in breast cancer survivors with persistent, post-treatment fatigue. It is anticipated that the Iyengar Yoga intervention will be feasible and acceptable to breast cancer survivors with minimal side effects and that the Yoga intervention will be effective in improving fatigue and physical performance.
|Study Design:||Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Single Blind (Outcomes Assessor)
Primary Purpose: Treatment
|Official Title:||Iyengar Yoga for Breast Cancer Survivors With Persistent Fatigue|
- Fatigue [ Time Frame: Measured at baseline, after the 12 week intervention and at 3 months post-intervention ] [ Designated as safety issue: No ]
- Secondary outcomes include depressed mood, sleep disturbance, pain, quality of life, and proinflammatory cytokine activity [ Time Frame: Measured at baseline, after the 12 week intervention and at 3 months post-intervention ] [ Designated as safety issue: No ]
|Study Start Date:||June 2008|
|Study Completion Date:||December 2010|
|Primary Completion Date:||October 2010 (Final data collection date for primary outcome measure)|
Other: Iyengar Yoga
The poses and breathing techniques to be used in this study are based on sequences developed by B.K.S. Iyengar for breast cancer survivors who suffer from fatigue. Women will start with simple versions of the poses and progress to more advanced versions over the course of the intervention.
Other Name: Yoga
Active Comparator: 2
A Wellness Seminar series
Other: Wellness Seminar Series
The Wellness Seminar Series consists of lectures on key topics, followed by group discussion. This series will focus entirely on cancer survivorship, including sessions on quality of life, side effects of cancer treatment, stress, nutrition and psychosocial issues.
Other Name: Health education
Fatigue is the most common and distressing side effect of cancer treatment and persists beyond successful treatment completion in approximately 30% of breast cancer survivors, causing serious disruption in quality of life. Behavioral interventions incorporating physical activity or relaxation/stress management have demonstrated beneficial effects on cancer-related fatigue, although research in cancer survivors is limited. Mind-body interventions such as yoga are extremely popular among cancer patients and offer a promising alternative to traditional treatments. Research is needed to establish the feasibility and efficacy of these interventions in cancer populations, particularly those who are experiencing problems with fatigue.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00727662
|United States, California|
|University of California, Cousins Center for PNI|
|Los Angeles, California, United States, 90095|
|Principal Investigator:||Julienne E Bower, Ph.D.||University of California, Los Angeles|