Flurbiprofen Axetil for Uterine Contraction Pain (FAUCOP)
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ClinicalTrials.gov Identifier: NCT00725218 |
Recruitment Status :
Completed
First Posted : July 30, 2008
Last Update Posted : August 6, 2008
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Condition or disease | Intervention/treatment | Phase |
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Postoperative Pain | Drug: Saline Drug: Flurbiprofen Axetil | Phase 4 |
Study Type : | Interventional (Clinical Trial) |
Actual Enrollment : | 97 participants |
Allocation: | Randomized |
Intervention Model: | Parallel Assignment |
Masking: | Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor) |
Primary Purpose: | Treatment |
Official Title: | Phase IV Study of Flurbiprofen Axetil for Uterine Contraction Pain After Abortion |
Study Start Date : | May 2008 |
Actual Primary Completion Date : | August 2008 |
Actual Study Completion Date : | August 2008 |

Arm | Intervention/treatment |
---|---|
Placebo Comparator: 1
Saline 5 ml injection 10 min prior to propofol administration.
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Drug: Saline
Saline 5 ml injection 10 min prior to propofol administration.
Other Name: Ringer's solution |
Experimental: 2
Flurbiprofen Axetil 50 mg in 5 ml injection 10min prior to propofol administration.
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Drug: Flurbiprofen Axetil
Flurbiprofen Axetil 50 mg in 5 ml injection 10min prior to propofol administration.
Other Name: KaiFen |
- VAS pain scorings [ Time Frame: At the end of the operation, 0,5,15,30,60min after operation ]
- Anesthetic consumptions [ Time Frame: At the end of the operation ]
- Overall VAS satisfaction scorings with analgesia [ Time Frame: At the end of the study ]
- Side effects [ Time Frame: During the whole period of the study ]
- Volume of bleeding [ Time Frame: At the end of the study ]

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Ages Eligible for Study: | 19 Years to 45 Years (Adult) |
Sexes Eligible for Study: | Female |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
- ASA status I-II
- Performing abortion operation (medical- or drug-induced
- Requiring painless abortion
Exclusion Criteria:
- < 19yrs, and >= 45yrs
- History of central active drugs administration
- Drug abuse
- Hypertension
- Diabetes
- Any other chronic diseases
- Allergy to the study drugs
- Habit of over-volume alcohol drinking
- Records of history of centrally active drug use and psychiatry
- Any organic disorders

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00725218
China, Jiangsu | |
Nanjing Maternal and Child Health Care Hospital | |
Nanjing, Jiangsu, China, 210004 |
Study Director: | XiaoFeng Shen, MD | Nanjing Medical University |
Responsible Party: | XiaoFeng Shen, Nanjing Maternal and Child Health Hospital |
ClinicalTrials.gov Identifier: | NCT00725218 |
Other Study ID Numbers: |
NMU-MZ203 M089732 |
First Posted: | July 30, 2008 Key Record Dates |
Last Update Posted: | August 6, 2008 |
Last Verified: | May 2008 |
NSAIDs Postoperative pain Analgesia Abortion |
Pain, Postoperative Postoperative Complications Pathologic Processes Pain Neurologic Manifestations Flurbiprofen Flurbiprofen axetil Analgesics Sensory System Agents |
Peripheral Nervous System Agents Physiological Effects of Drugs Anti-Inflammatory Agents, Non-Steroidal Analgesics, Non-Narcotic Anti-Inflammatory Agents Antirheumatic Agents Cyclooxygenase Inhibitors Enzyme Inhibitors Molecular Mechanisms of Pharmacological Action |