The Effect of Acupuncture on Pregnancy Rates in Women Undergoing Embryo Transfer (AcuIVF)

This study has been terminated.
(Recent abstract publication questioning the need for our study)
Information provided by (Responsible Party):
Ottawa Fertility Centre Identifier:
First received: July 23, 2008
Last updated: July 7, 2015
Last verified: July 2015
The present study is designed to test the hypothesis that acupuncture, before and after embryo transfer, significantly improves pregnancy rates, compared to embryo transfer with sham acupuncture and no acupuncture at all.

Condition Intervention Phase
Procedure: Active acupuncture
Procedure: Sham acupuncture
Phase 4

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
Official Title: The Effect of Acupuncture on Pregnancy Rates in Women Undergoing Embryo Transfer After in Vitro Fertilization: A Prospective Randomized Sham-controlled Trial

Resource links provided by NLM:

Further study details as provided by Ottawa Fertility Centre:

Primary Outcome Measures:
  • Clinical Pregnancy [ Time Frame: 4-5 weeks after treatment ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Live birth [ Time Frame: 9 months after treatment ] [ Designated as safety issue: No ]
  • Implantation rate [ Time Frame: 4-5 weeks after treatment ] [ Designated as safety issue: No ]
  • Side effects with acupuncture treatment [ Time Frame: 2 weeks after treatment ] [ Designated as safety issue: Yes ]

Enrollment: 30
Study Start Date: August 2008
Study Completion Date: May 2009
Primary Completion Date: May 2009 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: 1
Active acupuncture
Procedure: Active acupuncture
Acupuncture 25 minutes before and after embryo transfer
Sham Comparator: 2
Sham Acupuncture- acupuncture at neutral points
Procedure: Sham acupuncture
Acupuncture at neutral points, 25 minutes before and after embryo transfer
No Intervention: 3
Embryo transfer with no acupuncture


Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • patient is undergoing embryo transfer after IVF or ICSI
  • patient has given informed consent to participate

Exclusion Criteria:

  • frozen embryo transfer
  • previous enrollment in study
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00722462

Canada, Ontario
Ottawa Fertility Centre
Ottawa, Ontario, Canada, K2C 3V4
Sponsors and Collaborators
Ottawa Fertility Centre
Study Chair: Arthur Leader, MD Ottawa Fertility Centre
Principal Investigator: Doron Shmorgun, MD Ottawa Fertility Centre
  More Information

Responsible Party: Ottawa Fertility Centre Identifier: NCT00722462     History of Changes
Other Study ID Numbers: OttawaFC 
Study First Received: July 23, 2008
Last Updated: July 7, 2015
Health Authority: Canada: Health Canada
Canada: Canadian Institutes of Health Research

Keywords provided by Ottawa Fertility Centre:
Acupuncture processed this record on May 23, 2016