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Depth of Anaesthesia and Cognitive Dysfunction

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ClinicalTrials.gov Identifier: NCT00719628
Recruitment Status : Completed
First Posted : July 22, 2008
Last Update Posted : April 7, 2009
Sponsor:
Information provided by:
Rigshospitalet, Denmark

Brief Summary:
The purpose of this study is to investigate if there is an association between the depth of anaesthesia and the presence of cognitive deterioration after surgery.

Condition or disease
Cognitive Dysfunction

Study Type : Observational
Actual Enrollment : 70 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Depth of Anaesthesia and Presence of Postoperative Cognitive Dysfunction
Study Start Date : September 2008
Actual Primary Completion Date : April 2009
Actual Study Completion Date : April 2009

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Anesthesia




Primary Outcome Measures :
  1. mean Cerebral state index in relation to postoperative cognitive dysfunction


Information from the National Library of Medicine

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Ages Eligible for Study:   60 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients above 60 years eligible for surgery
Criteria

Inclusion Criteria:

  • Age above 60
  • Surgery in general anesthesia
  • surgery > 1 hour
  • ASA: 1-3

Exclusion Criteria:

  • Dementia
  • Excessive Use of alcohol or anxiolytics
  • Unable to understand danish
  • MMSE score < 24

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00719628


Locations
Denmark
Dep Anaesthesia, HOC, Rigshospitalet
Copenhagen, Denmark, 2100
Sponsors and Collaborators
Rigshospitalet, Denmark
Investigators
Study Director: Lars S Rasmussen, MD, PhD Dep anaesthesia, HOC, Rigshospitalet

Responsible Party: Jacob Steinmetz, Dep Anaesthesia, HOC 4231, Rigshospitalet
ClinicalTrials.gov Identifier: NCT00719628     History of Changes
Other Study ID Numbers: JAS-001
First Posted: July 22, 2008    Key Record Dates
Last Update Posted: April 7, 2009
Last Verified: April 2009

Keywords provided by Rigshospitalet, Denmark:
Postoperative
Cognitive
Dysfunction

Additional relevant MeSH terms:
Cognitive Dysfunction
Cognition Disorders
Neurocognitive Disorders
Mental Disorders