Molecular Analysis of Retinoblastoma
|ClinicalTrials.gov Identifier: NCT00718783|
Recruitment Status : Completed
First Posted : July 21, 2008
Last Update Posted : December 14, 2016
|Condition or disease||Intervention/treatment|
|Retinoblastoma||Other: Tissue samples taken from retinoblastoma Other: 5 ml peripheral blood|
|Study Type :||Observational|
|Actual Enrollment :||41 participants|
|Official Title:||Molecular Analysis of Retinoblastoma|
|Study Start Date :||April 2007|
|Actual Primary Completion Date :||December 2016|
|Actual Study Completion Date :||December 2016|
Other: Tissue samples taken from retinoblastoma
Tissue bankingOther: 5 ml peripheral blood
White blood cells will be isolated from the blood sample as a source of genomic DNA.
- Identify genes exhibiting differential expression within intraocular disease tissue between patients having only intraocular involvement and those having extraocular involvement. [ Time Frame: Indefinite ]
Biospecimen Retention: Samples With DNA
- Each tumor sample will be immediately transferred to a sterile cryovial and flash frozen in liquid nitrogen.
- White blood cells will be isolated from the blood sample as a source of genomic DNA.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00718783
|Hospital Calvo Mackenna|
|Hospital Escuela Bloque Materno Infantil|
|Principal Investigator:||Rachel Brennan, MD||St. Jude Children's Research Hospital|