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Epidemiology of Depression, Anxiety, and Cognitive Impairment

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ClinicalTrials.gov Identifier: NCT00717041
Recruitment Status : Completed
First Posted : July 16, 2008
Results First Posted : June 15, 2015
Last Update Posted : June 15, 2015
Sponsor:
Collaborator:
National Institute on Aging (NIA)
Information provided by (Responsible Party):
Manish Shah, University of Rochester

Brief Summary:

Many older adults have undetected health problems and lack basic prevention measures. Failure to identify and treat these conditions can lead to unnecessary morbidity and mortality and a decreased quality of life. Traditional screening and intervention programs, usually based in primary care providers' offices, have been insufficient, particularly in medically underserved populations. Alternate sites for screening and intervention have begun to receive attention and may hold promise.

The emergency department (ED) is the entry point for access to medical and social services for many patients and has the potential to serve as a site to identify older adults with unmet needs. However, we do not know the prevalence of depression and cognitive impairment and how they differ by mode of arrival of the patient to the ED. Second, a question remains as to the validity of screening patients during an acute illness. Upon completion, this study will describe the epidemiology of the population of older adults presenting to the ED.


Condition or disease
Depression Anxiety Cognitive Impairment

Detailed Description:

Many older adults have undetected health problems and lack basic prevention measures. Failure to identify and treat these conditions can lead to unnecessary morbidity and mortality and a decreased quality of life. Traditional screening and intervention programs, usually based in primary care providers' offices, have been insufficient, particularly in medically underserved populations. Alternate sites for screening and intervention have begun to receive attention and may hold promise.

The emergency department (ED) is the entry point for access to medical and social services for many patients and has the potential to serve as a site to identify older adults with unmet needs. However, we do not know the prevalence of depression and cognitive impairment and how they differ by mode of arrival of the patient to the ED. Second, a question remains as to the validity of screening patients during an acute illness. This study aims to:

  1. Compare the prevalence of depression and cognitive impairment among patients who arrive at the ED by EMS, as compared to those arriving via other means.
  2. Evaluate the reliability of screening patients for depression and cognitive impairment during an acute illness and after the illness.
  3. To evaluate correlates of depression, anxiety and suicidal ideation. Upon completion, this study will describe the epidemiology of the population of older adults presenting to the ED.

Study Type : Observational
Actual Enrollment : 1206 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Epidemiology of Depression, Anxiety, and Cognitive Impairment Among Emergency Department Patients
Study Start Date : May 2008
Actual Primary Completion Date : September 2008
Actual Study Completion Date : February 2009

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Anxiety
U.S. FDA Resources

Group/Cohort
Presenting to the ED
Patients who present to the ED



Primary Outcome Measures :
  1. Participants With Depression by Patient Health Questionnaire - 9 [ Time Frame: 2 hours ]
    Number of participants with depression as measured by the Patient Health Questionnaire - 9, with a score of greater than or equal to 10.

  2. Participants With Cognitive Impairment by Six Item Screener [ Time Frame: 2 hours ]
    Number of participants with cogintiive impairment as measured by the Six Item Screener, with greater than 2 questions incorrect

  3. Participants With Anxiety by Generalized Anxiety Disorder - 7 [ Time Frame: 2 hours ]
    Participants with anxiety as measured by the Generalized Anxiety Disorder - 7, with a score greater than or equal to 10.


Secondary Outcome Measures :
  1. Depression and Cognitive Impairment at 2 Weeks [ Time Frame: 2 weeks ]
    For the individuals who are able to be contacted in 2 weeks, how many still test positive for depression and cognitive impairment.



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Ages Eligible for Study:   60 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
All older adults arriving at participating hospital emergency departments to obtain emergency care.
Criteria

Inclusion Criteria:

  • Age 60 and older
  • Arrival at ED

Exclusion Criteria:

  • Institutionalized

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00717041


Locations
United States, New York
University of Rochester
Rochester, New York, United States, 14646
Sponsors and Collaborators
University of Rochester
National Institute on Aging (NIA)
Investigators
Principal Investigator: Manish N. Shah, MD MPH University of Rochester

Responsible Party: Manish Shah, Professor, University of Rochester
ClinicalTrials.gov Identifier: NCT00717041     History of Changes
Other Study ID Numbers: RSRB 24085
NIH 5K23AG028942
First Posted: July 16, 2008    Key Record Dates
Results First Posted: June 15, 2015
Last Update Posted: June 15, 2015
Last Verified: June 2015

Keywords provided by Manish Shah, University of Rochester:
Depression
Anxiety
Cognitive Impairment
Emergency medicine
prehospital care

Additional relevant MeSH terms:
Depression
Depressive Disorder
Anxiety Disorders
Cognitive Dysfunction
Behavioral Symptoms
Mood Disorders
Mental Disorders
Cognition Disorders
Neurocognitive Disorders