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Heat Stress and Volume Administration

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ClinicalTrials.gov Identifier: NCT00714766
Recruitment Status : Completed
First Posted : July 14, 2008
Last Update Posted : February 16, 2009
Sponsor:
Information provided by:
Rigshospitalet, Denmark

Brief Summary:
Heat stress reduces the central blood volume and causes orthostatic intolerance. The hypothesis is that infusion of volume may reduce effects of orthostatic stress during heat stress.

Condition or disease Intervention/treatment Phase
Syncope Procedure: Intravascular volume administration Not Applicable

Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 10 participants
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Basic Science
Official Title: Heat Stress and Volume Administration
Study Start Date : July 2008
Actual Primary Completion Date : August 2008
Actual Study Completion Date : August 2008

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Arm Intervention/treatment
Experimental: A Procedure: Intravascular volume administration
Infusion of colloid to reestablish CVP under heat stress



Primary Outcome Measures :
  1. Cardiac filling pressure in relation to cardiac SV [ Time Frame: with varying degress of lower body negative pressures ]


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Ages Eligible for Study:   18 Years to 40 Years   (Adult)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Age > 18 < 40

Exclusion Criteria:

  • Abnormal medical history

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To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00714766


Locations
Denmark
Dept of anesthesiology 2041
Copenhagen, Denmark, 2100
Sponsors and Collaborators
Rigshospitalet, Denmark
Investigators
Study Director: Niels Secher, MD, PhD Rigshospitalet, Denmark

Responsible Party: Niels Secher, Professor, Righospitale
ClinicalTrials.gov Identifier: NCT00714766     History of Changes
Other Study ID Numbers: Heat stress RH08
First Posted: July 14, 2008    Key Record Dates
Last Update Posted: February 16, 2009
Last Verified: February 2009

Additional relevant MeSH terms:
Syncope
Heat Stress Disorders
Unconsciousness
Consciousness Disorders
Neurobehavioral Manifestations
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms
Wounds and Injuries