Efficacy of Transference-Focused Psychotherapy for Borderline Personality Disorder
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|ClinicalTrials.gov Identifier: NCT00714311|
Recruitment Status : Completed
First Posted : July 14, 2008
Results First Posted : February 16, 2015
Last Update Posted : February 16, 2015
|Condition or disease||Intervention/treatment|
|Borderline Personality Disorder||Behavioral: Transference-Focused Psychotherapy Behavioral: treatment by experienced community psychotherapists|
Borderline personality disorder represents a sever clinical condition that affects 1-2% of the community and is characterized by a pervasive instability of interpersonal relationships, self-image, and affects, as well as a marked impulsivity; up to 10% of the patients commit suicide.
Transference-Focused Psychotherapy (TFP) is one psychotherapeutic approach among five that have been manualized and evaluated in RCTs. So far, TFP has not been compared to a control condition which is a crucial step in the evaluation of the efficacy of a psychosocial intervention.
This study is an RCT that compares one year of outpatient TFP to treatment by experienced community psychotherapists for borderline personality disorder.
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||104 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Single (Outcomes Assessor)|
|Official Title:||A Randomized-Controlled Trial of Transference-Focused Psychotherapy vs. Treatment by Experienced Community Psychotherapists for Borderline Personality Disorder|
|Study Start Date :||October 2004|
|Primary Completion Date :||February 2009|
|Study Completion Date :||February 2015|
Active Comparator: TFP
Behavioral: Transference-Focused Psychotherapy
Outpatient psychotherapy according to the treatment manual, sessions of 50 minutes twice per week
Active Comparator: ECP
treatment by experienced community psychotherapists
Behavioral: treatment by experienced community psychotherapists
Outpatient psychotherapy in private practices or outpatient units of psychiatric hospitals. Licensed psychotherapists with experience and special interest in the treatment of borderline patients are treating according to the method they have learned.
- Drop-out [ Time Frame: 1 year ]Did not finish one year of treatment.
- Suicidality (Suicide Attempts) [ Time Frame: 1 year ]
- Psychosocial Functioning (Global Assessment of Functioning, GAF-Score) [ Time Frame: 1 year ]
- Level of Personality Organization (Structured Interview for Personality Organization, STIPO) [ Time Frame: 1 year ]
- Number of Self-harming Acts [ Time Frame: 1 year ]
- Self-assessment of Psychopathology (BDI, STAI, BSI) [ Time Frame: 1 year ]
- Attachment Style and Reflective Function (Adult Attachment Interview, AAI) [ Time Frame: 1 year ]
- Borderline Symptomatology (DSM-IV Criteria) [ Time Frame: 1 month ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00714311
|Dept. of Psychoanalysis and Psychotherapy, Medical University Vienna|
|Vienna, Austria, 1090|
|Dept. of Psychiatry, Technical University of Munich|
|Munich, Bavaria, Germany, 81675|
|Principal Investigator:||Stephan Doering, MD||University of Muenster, Germany|