Efficacy of Transference-Focused Psychotherapy for Borderline Personality Disorder
|Borderline Personality Disorder||Behavioral: Transference-Focused Psychotherapy Behavioral: treatment by experienced community psychotherapists|
|Study Design:||Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Outcomes Assessor)
Primary Purpose: Treatment
|Official Title:||A Randomized-Controlled Trial of Transference-Focused Psychotherapy vs. Treatment by Experienced Community Psychotherapists for Borderline Personality Disorder|
- Drop-out [ Time Frame: 1 year ]Did not finish one year of treatment.
- Suicidality (Suicide Attempts) [ Time Frame: 1 year ]
- Psychosocial Functioning (Global Assessment of Functioning, GAF-Score) [ Time Frame: 1 year ]
- Level of Personality Organization (Structured Interview for Personality Organization, STIPO) [ Time Frame: 1 year ]
- Number of Self-harming Acts [ Time Frame: 1 year ]
- Self-assessment of Psychopathology (BDI, STAI, BSI) [ Time Frame: 1 year ]
- Attachment Style and Reflective Function (Adult Attachment Interview, AAI) [ Time Frame: 1 year ]
- Borderline Symptomatology (DSM-IV Criteria) [ Time Frame: 1 month ]
|Study Start Date:||October 2004|
|Study Completion Date:||February 2015|
|Primary Completion Date:||February 2009 (Final data collection date for primary outcome measure)|
Active Comparator: TFP
Behavioral: Transference-Focused Psychotherapy
Outpatient psychotherapy according to the treatment manual, sessions of 50 minutes twice per week
Active Comparator: ECP
treatment by experienced community psychotherapists
Behavioral: treatment by experienced community psychotherapists
Outpatient psychotherapy in private practices or outpatient units of psychiatric hospitals. Licensed psychotherapists with experience and special interest in the treatment of borderline patients are treating according to the method they have learned.
Borderline personality disorder represents a sever clinical condition that affects 1-2% of the community and is characterized by a pervasive instability of interpersonal relationships, self-image, and affects, as well as a marked impulsivity; up to 10% of the patients commit suicide.
Transference-Focused Psychotherapy (TFP) is one psychotherapeutic approach among five that have been manualized and evaluated in RCTs. So far, TFP has not been compared to a control condition which is a crucial step in the evaluation of the efficacy of a psychosocial intervention.
This study is an RCT that compares one year of outpatient TFP to treatment by experienced community psychotherapists for borderline personality disorder.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00714311
|Dept. of Psychoanalysis and Psychotherapy, Medical University Vienna|
|Vienna, Austria, 1090|
|Dept. of Psychiatry, Technical University of Munich|
|Munich, Bavaria, Germany, 81675|
|Principal Investigator:||Stephan Doering, MD||University of Muenster, Germany|