Embryo Aneuploidies and Ovarian Stimulation
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|ClinicalTrials.gov Identifier: NCT00707525|
Recruitment Status : Completed
First Posted : July 1, 2008
Last Update Posted : March 26, 2010
There is a considerable concern about the effects of controlled ovarian hyperstimulation (COH) for In Vitro Fertilization- Embryo Transfer (IVF-ET) on embryo quality and on the incidence of chromosomal abnormalities in oocytes and embryos.
The main question remaining is if COH may increase the aneuploidies rate in young and healthy women. Therefore, the primary endpoint of the present study is to analyse the incidence of chromosomal abnormalities in this group of patients (oocyte donors), either in oocytes obtained after a natural cycle or in those retrieved after a COH cycle. To get rid of the male factor influence, donated sperm will be used.
|Condition or disease||Intervention/treatment||Phase|
|Embryo Aneuploidies||Procedure: Preimplantation Genetic Diagnosis||Phase 4|
|Study Type :||Interventional (Clinical Trial)|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Official Title:||Incidence of EmbyoO Aneuploidies in Natural Versus Stimulated Cycles in the Same Women.|
|Study Start Date :||February 2008|
|Primary Completion Date :||February 2010|
|Study Completion Date :||February 2010|
No Intervention: 1
Natural cycle oocyte donation
Active Comparator: 2
Stimulated cycle oocyte donation.
Procedure: Preimplantation Genetic Diagnosis
Preimplantation Genetic Diagnosis (PGD) is performed on the embryos resulting from these natural and stimulated cycles.
- Embryo aneuploidies [ Time Frame: 2 cycles ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00707525
|Instituto Valenciano de Infertilidad|
|Valencia, Spain, 46015|