Tear Dynamics After Restasis Treatment in Dry Eye Patients
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Increase in tear volume after the 3-month treatment and returned to baseline during 6-month follow-up after discontinuation of study treatment. [ Time Frame: 3 months for treatment and follow-up of 6 months after discontinuation of study treatment. ]
Tear meniscus volume after treatment [ Time Frame: 3 months ]
Significant increase in tear meniscus volume was found in patients after 3 months of treatment.
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Ages Eligible for Study:
18 Years to 90 Years (Adult, Senior)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
dry eye patients more than 18 yrs old
The participant will be eligible for entry in the study if s/he:
Is at least 18 years old and has full legal capacity to volunteer;
Has read and signed the IRB Informed Consent Document;
Is willing and able to follow participant instructions;
Has clear corneas;
Has 20/100 uncorrected visual acuity or better;
Has dry eye according to the study definition of DES (study subjects);
Has not use Restasis within 3 months.
The subjects will ineligible for entry into the study if s/he:
Has any systemic disease affecting ocular health except for Sjögren's syndrome;
Is using any systemic or topical medications that will affect ocular health except for artificial tears;
Has an active ocular disease other than DES, or Sjögren's syndrome
Has any clinically significant lid or conjunctival abnormalities, neovascularization, corneal scars or corneal opacities;
Has limbal or bulbar injection or corneal staining that was clinically significant, which are not due to DES;
Has worn rigid gas permeable lenses within 1 year and during the study;
Has had surgery or an eye injury within 6 months;
Was a soft contact lens wearer within 2 weeks and during the study.