Intravitreal Bevacizumab for Diabetic Macular Edema

This study is enrolling participants by invitation only.
Information provided by:
Isfahan Ophthalmology Research Center Identifier:
First received: June 20, 2008
Last updated: NA
Last verified: June 2008
History: No changes posted

Diabetic macular edema is a common cause of visual loss among diabetic patients. Studies have demonstrated the role of vascular endothelial growth factor (VEGF) in the pathogenesis of edema.

This study designed to evaluate the effect of Intravitreal injection of a recombinant monoclonal anti-VEGF antibody, Bevacizumab, for treatment of diabetic macular edema.

Condition Intervention Phase
Macular Edema
Diabetic Retinopathy
Drug: Bevacizumab
Phase 2
Phase 3

Study Type: Interventional

Resource links provided by NLM:

Further study details as provided by Isfahan Ophthalmology Research Center:


Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Diabetes mellitus
  • Clinically significant macular edema
  • Possibility of performing macular OCT
  • Consent of patient for inclusion in the study

Exclusion Criteria:

  • History of macular photocoagulation in less than 6 months of inclusion in the study
  • Necessity of surgical intervention
  • Rejection of the remaining in the study by patient
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

No Contacts or Locations Provided
  More Information Identifier: NCT00703235     History of Changes
Other Study ID Numbers: MUI - clinical - 185290 
Study First Received: June 20, 2008
Last Updated: June 20, 2008
Health Authority: Iran: Ministry of Health

Additional relevant MeSH terms:
Diabetic Retinopathy
Macular Edema
Cardiovascular Diseases
Diabetes Complications
Diabetes Mellitus
Diabetic Angiopathies
Endocrine System Diseases
Eye Diseases
Macular Degeneration
Retinal Degeneration
Retinal Diseases
Vascular Diseases
Angiogenesis Inhibitors
Angiogenesis Modulating Agents
Antineoplastic Agents
Growth Inhibitors
Growth Substances
Physiological Effects of Drugs processed this record on May 26, 2016