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Diagnostic and Interventional Therapy in Acute Pancreatitis

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ClinicalTrials.gov Identifier: NCT00699933
Recruitment Status : Unknown
Verified June 2010 by University of Regensburg.
Recruitment status was:  Recruiting
First Posted : June 18, 2008
Last Update Posted : August 9, 2011
Sponsor:
Information provided by:
University of Regensburg

Brief Summary:
The study aims to evaluate the course of patients with acute pancreatitis. Thereby we analyze different diagnostics and compare ultrasound, MRI and CT-scan in detection of necrotic areas and evaluate interventional therapy methods like percutaneous drainage techniques regarding the outcome. Laboratory values were assessed as well.

Condition or disease Intervention/treatment
Acute Pancreatitis Other: CT-guided percutaneous drainage technique

Detailed Description:
For laboratory values different inflammation markers were measured and compared.

Study Type : Observational
Estimated Enrollment : 50 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Diagnostic and Interventional Therapy in Acute Pancreatitis
Study Start Date : May 2008
Estimated Primary Completion Date : December 2012
Estimated Study Completion Date : December 2012

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Pancreatitis
U.S. FDA Resources

Group/Cohort Intervention/treatment
1
Evaluation of one study cohort
Other: CT-guided percutaneous drainage technique
Evaluation of different diagnostics and evaluation of outcome of patients who received percutaneous CT-guided drainage for necrotic debridement and analyze the further outcome



Primary Outcome Measures :
  1. Length of hospital stay [ Time Frame: weekly ]

Secondary Outcome Measures :
  1. time to surgery [ Time Frame: weekly ]
  2. active necrosectomy [ Time Frame: weekly ]
  3. ICU stay [ Time Frame: weekly ]

Biospecimen Retention:   Samples With DNA
Bacterial DNA


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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
50 patients with acute pancreatitis
Criteria

Inclusion Criteria:

  • Age > 18 years
  • Acute pancreatitis
  • Written formal consent

Exclusion Criteria:

  • Pregnancy
  • Missing formal consent
  • Individual contraindications for CT-scan
  • MRI or endoscopic ultrasound

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00699933


Contacts
Contact: Tanja Bruennler, Dr. med. +49-941-944 ext 7010 tanja.bruennler@klinik.uni-r.de

Locations
Germany
Department of Internal medicine I, University of Regensburg Recruiting
Regensburg, Germany, 93053
Contact: Tanja Bruennler, Dr. med.    +43-941-944 ext 7010    tanja.bruennler@klinik.uni-r.de   
Principal Investigator: Tanja Bruennler, Dr. med.         
Sponsors and Collaborators
University of Regensburg
Investigators
Study Director: Jürgen Schölmerich, Prof. Director of Department of Internal Medicine I
Study Director: Stefan Feuerbach, Prof. Director of Department of Radiology

Responsible Party: Dr. Tanja Brünnler, University of Regensburg
ClinicalTrials.gov Identifier: NCT00699933     History of Changes
Other Study ID Numbers: 08/008
First Posted: June 18, 2008    Key Record Dates
Last Update Posted: August 9, 2011
Last Verified: June 2010

Keywords provided by University of Regensburg:
acute pancreatitis
interventional therapy
CT-guided drainage therapy
percutaneous necrosectomy
Comparison of different diagnostic procedures: MRI, CT, Ultrasound
Evaluation of interventional therapy including percutaneous drainage techniques und necrosectomies

Additional relevant MeSH terms:
Pancreatitis
Pancreatic Diseases
Digestive System Diseases