Try our beta test site
IMPORTANT: Listing of a study on this site does not reflect endorsement by the National Institutes of Health. Talk with a trusted healthcare professional before volunteering for a study. Read more...

Excimer Lamp Versus Excimer Laser in Vitiligo Treatment

This study has been completed.
Information provided by:
Centre Hospitalier Universitaire de Nice Identifier:
First received: June 10, 2008
Last updated: October 30, 2008
Last verified: October 2008

308 nm excimer lamp and 308 nm excimer laser have both provide interesting results in treating vitiligo. They have the same wavelength but the type of emission of the photons is different. To date there is no direct comparative data concerning these two devices in this indication.

The aim of the study is to make an intra-individual prospective comparison between these two phototherapies.

Condition Intervention Phase
Radiation: 308nm excimer lamp
Radiation: 308nm excimer laser
Phase 3

Study Type: Interventional
Official Title: Comparative Study of 308nm Excimer Lamp and 308nm Excimer Laser in the Treatment of Vitiligo

Resource links provided by NLM:

Further study details as provided by Centre Hospitalier Universitaire de Nice:

Primary Outcome Measures:
  • Repigmentation rate in the treated areas [ Time Frame: 12 weeks ]

Secondary Outcome Measures:
  • Tolerance and safety of the treatments [ Time Frame: 12 weeks ]

Arms Assigned Interventions
Active Comparator: A
308 nm excimer lamp
Radiation: 308nm excimer lamp
50 mJ/cm² below the MED (minimal erythemal dose) and progressive increase Twice a week for 12 weeks
Active Comparator: B
308 nm excimer laser
Radiation: 308nm excimer laser
50 mJ/cm² below the MED (minimal erythemal dose) and progressive increase Twice a week for 12 weeks (same doses will be used between the 2 arms)


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • patient above 18
  • vitiligo for more than 3 months
  • at least 2 vitiligo symmetric patches more than 10cm²
  • to read and understand the inform consent
  • to have a social security number
  • non pregnant for women

Exclusion Criteria:

  • pregnant women
  • keloids
  • history of radiotherapy or skin cancer in the treated areas
  • treatment for vitiligo in the past 4 weeks
  • phototherapy in the past 12 weeks; history of photodermatosis
  • treatment inducing photosensibilization
  • immunosuppression
  • patient who participated in a study in the past 3 months
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00696358

Department of Dermatology, University Hospital of Nice
Nice, France, 06200
Sponsors and Collaborators
Centre Hospitalier Universitaire de Nice
  More Information Identifier: NCT00696358     History of Changes
Other Study ID Numbers: NICE-VIT1
Study First Received: June 10, 2008
Last Updated: October 30, 2008

Keywords provided by Centre Hospitalier Universitaire de Nice:

Additional relevant MeSH terms:
Pigmentation Disorders
Skin Diseases processed this record on May 23, 2017