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Impact of General Anaesthetics on Excitability of the Peripheral Sensory Nerve

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ClinicalTrials.gov Identifier: NCT00696254
Recruitment Status : Completed
First Posted : June 12, 2008
Last Update Posted : June 3, 2009
Sponsor:
Information provided by:
University of Zurich

Brief Summary:
The aim of this study is to investigate the effect of general anaesthetics on nerve excitability. We use the method of threshold tracking to measure selected parameters of nerve excitability.

Condition or disease Intervention/treatment
Scheduled for Surgery Behavioral: Nerve excitability measurement

Study Type : Observational
Observational Model: Case Control
Time Perspective: Prospective
Study Start Date : March 2008
Study Completion Date : December 2008




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Ages Eligible for Study:   18 Years to 75 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Inclusion criteria: German speaking patients scheduled for surgery under general anaesthesia
Criteria

Inclusion criteria: German speaking patients scheduled for surgery under general anaesthesia.

Weight 50 - 100 kg signed informed consent

Exclusion criteria: 1. known peripheral neuropathy 2. Diabetes mellitus 3. Neuro-psychiatric Diagnosis 4. pregnant/ breast-feeding women 5. congestive heart disease 6. more than 2 risk factors (out of 4) for PONV (female, non-smoker, known PONV, opioids postoperatively) 7. participants of other studies 8. inability of verbal expression


Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00696254


Locations
Switzerland
University Hospital Zurich
Zurich, Switzerland
Sponsors and Collaborators
University of Zurich
Investigators
Study Director: 01 Studienregister MasterAdmins UniversitaetsSpital Zuerich

ClinicalTrials.gov Identifier: NCT00696254     History of Changes
Other Study ID Numbers: 5-2008
First Posted: June 12, 2008    Key Record Dates
Last Update Posted: June 3, 2009
Last Verified: June 2009