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Impact of General Anaesthetics on Excitability of the Peripheral Sensory Nerve

This study has been completed.
Information provided by:
University of Zurich Identifier:
First received: March 17, 2008
Last updated: June 2, 2009
Last verified: June 2009
The aim of this study is to investigate the effect of general anaesthetics on nerve excitability. We use the method of threshold tracking to measure selected parameters of nerve excitability.

Condition Intervention Phase
Scheduled for Surgery
Behavioral: Nerve excitability measurement
Phase 1

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective

Further study details as provided by University of Zurich:

Study Start Date: March 2008
Estimated Study Completion Date: December 2008

Ages Eligible for Study:   18 Years to 75 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Inclusion criteria: German speaking patients scheduled for surgery under general anaesthesia

Inclusion criteria: German speaking patients scheduled for surgery under general anaesthesia.

Weight 50 - 100 kg signed informed consent

Exclusion criteria: 1. known peripheral neuropathy 2. Diabetes mellitus 3. Neuro-psychiatric Diagnosis 4. pregnant/ breast-feeding women 5. congestive heart disease 6. more than 2 risk factors (out of 4) for PONV (female, non-smoker, known PONV, opioids postoperatively) 7. participants of other studies 8. inability of verbal expression

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Please refer to this study by its identifier: NCT00696254

University Hospital Zurich
Zurich, Switzerland
Sponsors and Collaborators
University of Zurich
Study Director: 01 Studienregister MasterAdmins UniversitaetsSpital Zuerich
  More Information Identifier: NCT00696254     History of Changes
Other Study ID Numbers: 5-2008
Study First Received: March 17, 2008
Last Updated: June 2, 2009 processed this record on April 28, 2017